molecular-biology

Almost all animal species -- including humans -- have blood cells, but between different species our blood tells different stories.

Nature Communications, Published online: 25 May 2026; doi:10.1038/s41467-026-73578-z AI-based inverse design of DNA origami has been limited by the scarcity of large, standardised datasets. Here, the authors present a diffusion-based design framework trained on simulated equilibrium conformations, highlighting the promise of generative AI models empowered by physical simulation for de novo design…

A new genealogical study shows how genetic analyses threading together DNA across centuries can save...

Scientists have uncovered a surprising twist in how cells behave when division goes wrong. Sometimes a cell successfully copies its DNA but fails to split into two, leaving it with double the genetic material — a mistake linked to aging, cancer, and other major diseases. Researchers discovered that not all of these failures are equal.

Nature, Published online: 25 May 2026; doi:10.1038/d41586-026-01621-6 Billie Goolsby’s experience with hearing loss helped her to develop a robotic tadpole for deciphering the secret lives of amphibians.

A rapidly advancing area of biomedical innovation is shining a spotlight on miR-128-3p, a small yet powerful molecule with the potential to reshape how diseases—especially cancer—are detected, monitored, and treated. This microRNA, part of a broader class of non-coding RNAs, plays a critical role in regulating gene activity and maintaining cellular homeostasis.

This book assembles experts from diverse fields to highlight aspects of and insights into epigenetics, RNA networking, virology, genetics, and cell biology that must be part of the Integrative Theory of Evolution. This theory illuminates how the abundance of epigenetic regulations, RNA group interactions, the role of viruses in cellular host organisms, and cell identity drive evolutionary process…

Scientific Reports, Published online: 25 May 2026; doi:10.1038/s41598-026-54526-9 Benchmarking the prediction of responding cells to perturbations affecting both gene expression and cellular abundance using scRNA sequencing

Scientific Data, Published online: 25 May 2026; doi:10.1038/s41597-026-07472-0 The near telomere-to-telomere genome of the Murray cod ( Maccullochella peelii )

resLens uses genomic language models to detect antibiotic resistance genes from DNA sequences, performing especially well on long-read data and on some ARGs poorly represented in reference databases.

Scientific Reports, Published online: 25 May 2026; doi:10.1038/s41598-026-54788-3 Reference-guided genome assembly of long non-coding rna transcripts reveals target genes associated with Crohn’s disease

Nature Communications, Published online: 25 May 2026; doi:10.1038/s41467-026-73122-z Intrahepatic cholestasis of pregnancy is a common liver disorder with poorly defined genetic causes. Here, the authors identify 26 risk loci through a large GWAS meta‑analysis, implicating bile acid and lipid metabolism pathways and revealing shared genetic architecture with pancreatitis.

A new review highlights how human evolution has shaped the presence of pathogenic variations in DNA damage repair (DDR) genes, offering a new perspective on why modern populations face increased cancer susceptibility.

International audience

International audience

_European Journal for Philosophy of Science_. forthcomingThis paper provides a philosophical examination of the integrative field of sociogenomics which seeks to incorporate genomic tools into social science research on individual outcomes. I characterise sociogenomic integration as being guided by two main promises, which I define as the promises of credibility and trustworthiness. I demonstrate…