neuroscience

The Mount Sinai Hospital / Mount Sinai School of Medicine
1h ago

Researchers found that TIMP2 supports microglial function and reduces age-related cellular changes associated with inflammation in mice. As the brain grows older, its immune cells can become less effective at clearing debris and controlling potentially harmful responses. Researchers at The Icahn School of Medicine at Mount Sinai have identified a role for TIMP2, a protein [...]

Findings from a new study by researchers at Columbia University Vagelos College of Physicians and Surgeons suggest that the trickle of neurons created in the adult hippocampus could be instrumental in preventing depression. Most of the brain’s 100 billion neurons are created before birth. Published in the journal Nature Medicine, the study shows for the […]

Nature Communications, Published online: 22 August 2026; doi:10.1038/s41467-026-76998-z Sex hormones and cancer-cell sex influence tumor growth, but other sex-dependent drivers of oncogenesis remain unclear. Here, the authors reveal that the sex of central neurons alters the peripheral tumor-supportive niche to promote tumor growth.

Swinburne researchers have discovered how broccoli could help treat an extremely rare and incurable disease that affects only about 200 Australians. A naturally occurring compound in broccoli is being investigated as a possible treatment for Friedreich ataxia, a rare nervous system disease. Research from Swinburne suggests the compound can act on biological processes involved in [...]

BackgroundPost-stroke depression (PSD) is the most common neuropsychiatric complication following stroke. Puerarin (PU), the principal bioactive compound extracted from the medicinal and edible plant Pueraria lobata, has shown beneficial therapeutic effects in both depression and stroke. However, the therapeutic effect of PU on PSD and its underlying mechanisms remain unclear. This study investig…

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