Thalamo-cortical synchrony shapes seizure expression in human temporal lobe epilepsy

Jorge Gonzalez-Martinez
Nature Communications, Published online: 25 May 2026; doi:10.1038/s41467-026-73053-9 In drug-resistant temporal lobe epilepsy, thalamo–cortical synchrony in the first 20 seconds after seizure onset is stronger in clinical than electrographic seizures, highlighting network engagement as a key driver of seizure symptoms.