Nature Communications

Nature Communications, Published online: 13 June 2026; doi:10.1038/s41467-026-74143-4 Researchers report a breakthrough in ultra-broadband magnonic frequency combs by driving a nonlinear YIG resonator far off-resonance, yielding over 350 comb lines across 450 MHz with continuously tunable spacing.

Nature Communications, Published online: 13 June 2026; doi:10.1038/s41467-026-74320-5 Spatial and single-cell transcriptomics of patient-derived brain organoids reveal disrupted progenitor–neuron organization and local neuronal disarray, implicating spatially mosaic pathogenesis in autism heterogeneity.

Nature Communications, Published online: 13 June 2026; doi:10.1038/s41467-026-74155-0 A Gaussian process framework integrates neighbourhood EV registration data with regional scenarios to generate probabilistic local adoption forecasts with uncertainty estimates for electricity network planning.

Nature Communications, Published online: 13 June 2026; doi:10.1038/s41467-026-74061-5 Inhibition of PLK4 is synthetic lethal in cancers with chromosome 17q TRIM37 copy number gain. Here, the authors show that while RP-1664 (PLK4 inhibitor) causes centrosome depletion in a TRIM37-dependent manner as high doses, low dose causes cell death in a TRIM37-independent manner via centrosome amplification …

Nature Communications, Published online: 13 June 2026; doi:10.1038/s41467-026-74318-z Mechanisms underlying effective immune escape in HPV-associated oropharyngeal cancers despite the presence of immune cells are incompletely understood. Here, authors use single-cell spatial analysis to show that tumors form distinct local immune niches, including hypoxic regions and chemokine foci, that shape im…

Nature Communications, Published online: 13 June 2026; doi:10.1038/s41467-026-74448-4 Here, the authors describe four distinct DNA sequence patterns in nucleosomes that shape how transcription factors interact with chromatin, revealing previously hidden DNA-encoded rules governing nucleosome positioning and gene regulation.

Nature Communications, Published online: 13 June 2026; doi:10.1038/s41467-026-74401-5 Paganos et al provide evidence suggesting that sea stars may share ancient ovarian cell types and signaling systems with mammals, offering new clues to how egg development and reproductive regulation evolved across animals.

Nature Communications, Published online: 13 June 2026; doi:10.1038/s41467-026-74384-3 The evolutionary changes in cancer genomes under treatment are not fully understood. Here, whole-genome sequencing of 58 single-cell tumoroids and 18 matched bulk tumours from 6 metastatic colorectal cancer patients reveals clonal structures and mutation patterns under therapy.

Nature Communications, Published online: 13 June 2026; doi:10.1038/s41467-026-74323-2 Using pharmacodynamic, genomic, and transcriptomic analyses, authors show that amoxicillin clavulanic acid selectively eradicates TEM-1-producing Escherichia coli in urinary tract infections by exploiting high urinary clavulanate exposure.

Nature Communications, Published online: 13 June 2026; doi:10.1038/s41467-026-74274-8 Humans show reproducible sex differences in regional cortical volume, area and thickness controlling for overall brain size. These regions are enriched for effects of potentially causal sex chromosomal and gonadal influences on cortical anatomy.

Nature Communications, Published online: 13 June 2026; doi:10.1038/s41467-026-73931-2 Bone metastases derived from lung cancer typically exhibit an immunosuppressive microenvironment. This study identifies a YBX1 glycosylation–dependent mechanism that drives both metastasis and immunosuppression, and proposes the small molecule Icaritin as a potential therapeutic strategy through YBX1 degradation.

Nature Communications, Published online: 13 June 2026; doi:10.1038/s41467-026-74074-0 Researchers use evolutionary game theory and human embryoids to show that competitive cell killing, though costly to individual cells, is a strategic behavior to maintain embryo size — suggesting competition underpins embryonic cooperation.

Nature Communications, Published online: 13 June 2026; doi:10.1038/s41467-026-74387-0 Okara, a major by-product of soybean processing, is generated at an estimated 140 million tonnes annually, with landfill disposal contributing to pollution and the loss of valuable organic resources. Conventional aerobic composting is land-intensive, slow, and associated with substantial greenhouse gas emissions…

Nature Communications, Published online: 13 June 2026; doi:10.1038/s41467-026-73579-y By swapping a single nitrogen atom for sulfur, researchers switched the enzyme KatG from its natural cofactor assembly to stereoselective sulfoxidation, revealing how atomic-level precision can reprogram complex enzymatic pathways.

Nature Communications, Published online: 13 June 2026; doi:10.1038/s41467-026-74218-2 Liang et al. present flexible semiconductive polyMOF membranes, created by copolymerizing metal–organic frameworks with polymers. This integration reduces structural defects and improves charge transport, enabling highly sensitive X-ray detection with leading sensitivity and a conformal design suited for flexibl…

Nature Communications, Published online: 13 June 2026; doi:10.1038/s41467-026-74224-4 The design and synthesis of molecules featuring both boron and silicon moieties hold significant promise for delivering unique reactivity patterns and material properties. Herein, the authors report a titaniumcatalyzed selective hydroboration of the C(sp3)–Si bonds in silacyclobutanes for the synthesis of boryl-…

Nature Communications, Published online: 13 June 2026; doi:10.1038/s41467-026-74219-1 This work demonstrates field-driven annealing of skyrmion lattices in van der Waals Fe3GaTe2. Magnetic-field oscillations and current pulses transform disordered skyrmions into distinct ordered states through a shared defect-mediated collective mechanism.

Nature Communications, Published online: 13 June 2026; doi:10.1038/s41467-026-74101-0 Predicting transition states of chemical reactions is demanding. A generative flow model in distance geometry space, dubbed TS-DFM, is proposed, achieving higher structural accuracy and better generalizability than Cartesian-based approaches.

Nature Communications, Published online: 13 June 2026; doi:10.1038/s41467-026-74340-1 Lithium metal batteries face challenges with dendritic growth. Here, authors employ in situ TEM to reveal how specific electrolyte anions dictate lithium nucleation and interphase architecture, establishing design principles for suppressing dendrites and enabling stable lithium deposition.

Nature Communications, Published online: 13 June 2026; doi:10.1038/s41467-026-74162-1 Alveolar macrophages can contribute to systemic anti-tumor responses. Here the authors describe a cascaded targeted liposomal nanomedicine for generating chimeric antigen receptor-modified alveolar macrophages via intrapulmonary nebulization, promoting anti-tumor immunity in lung cancer models.