synthetic-biology

Further reading. https://academic.oup.com/brain/advanc… https://doi.org/10.1093/brain/awae150 #organoids #sciencenews #brainorganoids #sentience #biocomputers #conciousness

Artificial symbiosis enables three-dimensional living materials to be produced with properties normally associated with organisms rather than industry – potentially changing how materials can be manufactured. The work could open new possibilities in areas ranging from wound healing and biological reactors to responsive materials that can repair themselves.

Delve into the fascinating world of organoid intelligence at XPANSE 2024 in Abu Dhabi. Presented by Dr. Thomas Hartung, Professor of Medical Microbiology at Johns Hopkins University, this session explores the cutting-edge research and potential of lab-grown organoids to revolutionize computing, medicine, and neuroscience. XPANSE, the world’s first visioning of the future with exponential technolo…

Nature Communications, Published online: 13 June 2026; doi:10.1038/s41467-026-73579-y By swapping a single nitrogen atom for sulfur, researchers switched the enzyme KatG from its natural cofactor assembly to stereoselective sulfoxidation, revealing how atomic-level precision can reprogram complex enzymatic pathways.

Using hundreds of thousands of neurons anchored to the device, the Science architecture connects to the brain with orders of magnitude more bandwidth than current state-of-the-art devices, while avoiding the damage and limitations of putting wires into a brain.

Not so long ago, DIY biology mostly meant extracting DNA from strawberries or growing mold in a petri dish for a school science project. Those experiments are still around, but the world of amateur biology has evolved considerably over the past decade.  Today, a growing network of community biology labs and citizen scientists is making biotechnology more […] The post DIY biology experiments: how …

Kidney transplantation remains the most effective treatment for end-stage kidney disease, yet a severe shortage of donor organs continues to limit access for millions of patients worldwide.

BackgroundThe blood-brain barrier (BBB) is a major obstacle to targeted drug delivery for central nervous system (CNS) diseases. Although liposomes and polymeric nanoparticles have improved brain drug delivery, limitations remain in BBB targeting, long-term biocompatibility, and in vivo clearance. Exosomes are endogenous nanoscale extracellular vesicles with favourable biocompatibility, low immun…

Detailed research-use protocol for human iPSC lentiviral transduction, including GFP monitoring, puromycin selection, clonal expansion, spin infection considerations, and QC. The post iPSC Lentiviral Transduction Protocol with GFP/Puromycin Selection appeared first on THE SCIENCE NOTES .

(NYT) – Researchers relied on a newer gene-editing technique that may make it possible to engineer embryos, a prospect that has long alarmed bioethicists. Scientists at Columbia University have edited the DNA of early human embryos with unprecedented accuracy, an … Read More

Nature Communications, Published online: 06 June 2026; doi:10.1038/s41467-026-74000-4 Mapping cell dynamics from static data is a challenge in genomics. Here, authors introduce ArchVelo, a computational method for modeling transcription dynamics and trajectory inference using chromatin accessibility archetypes in single-cell multi-omics, and infer new T cell transitions in infection.

A team at Northwestern University has developed printable artificial neurons capable of triggering real neural activity in living tissue, according to a study published in Nature Nanotechnology. The finding matters because lab-built hardware isn’t just simulating brain signaling but producing responses indistinguishable enough from biological signals that actual neurons react to them. Led by prof…

Northwestern Medicine scientists have developed a novel synthetic biomolecular condensate that can degrade intracellular disease-causing proteins, providing a framework for new therapeutic approaches for a wide range of diseases, as detailed in a recent study published in Nature Communications. Shana Kelley, Ph.D., the Neena B. Schwartz Professor of Chemistry, Biomedical Engineering, and Biochemi…

Nature Communications, Published online: 05 June 2026; doi:10.1038/s41467-026-73990-5 Cells carry DNA and RNA signatures that mark disease states, but few tools can both sense them in living cells and link detection to cellular outputs. Here, the authors develop SONAR, which uses target-dependent ssDNA ligation inside cells to detect nucleic acids and drive programmable gene-control outputs.

Diarrheal diseases, such as yellow dysentery and white dysentery caused by pathogens or viruses, in newborn piglets lead to substantial economic losses in the swine industry worldwide. Gut microbiota dysbiosis is frequently observed in diarrheic piglets and is thought to play a role in disease pathogenesis, although causal relationships remain to be established. However, developing reliable micro…

A team of scientists from across Asia has launched an ambitious project to create artificial living cells from non-living materials within the next decade. If successful, the effort could transform biology, medicine, and biotechnology while helping scientists answer one of humanity’s biggest questions: What is life? The project is being led by researchers from the […] The post Scientists launch 1…

Northwestern Medicine scientists have developed a novel synthetic biomolecular condensate that can target and degrade intracellular disease-causing proteins, providing a framework for new therapeutic approaches for a wide range of diseases, as detailed in a recent study. The post Novel Synthetic Biomolecule Degrades Disease-Related Proteins appeared first on News Center .