synthetic-biology

Nature Communications, Published online: 25 May 2026; doi:10.1038/s41467-026-73578-z AI-based inverse design of DNA origami has been limited by the scarcity of large, standardised datasets. Here, the authors present a diffusion-based design framework trained on simulated equilibrium conformations, highlighting the promise of generative AI models empowered by physical simulation for de novo design…

International audience

International audience

Scientists have created an AI-powered system that can scan and map an entire mouse body in extraordinary detail — and it just uncovered a surprising new effect of obesity. Beyond disrupting metabolism, obesity appears to damage facial sensory nerves linked to touch and sensation, while also triggering widespread inflammation across the body.

A biotech company that aims to resurrect lost creatures says it has hatched live chicks in an artificial environment

Nature Communications, Published online: 23 May 2026; doi:10.1038/s41467-026-73618-8 Genetic code expansion can be limited by the need to supply non-standard amino acids. The authors design bacteria that perform integrated steps of converting supplemented aldehydes to L-phenylalanine derivatives and incorporating them within proteins.

This preprint investigates the hypothesis that viable heterogeneous systems may belong to a broader structural proportionality family, termed the Congruity Invariance Class. Rather than claiming a universal fixed equation, the work evaluates whether interpretable proportional structures repeatedly emerge across heterogeneous domains including breast cancer morphology classification, external unse…

Abstract Arsenic trioxide has recently been approved for the treatment of acute promyelocytic leukemia, but it is also a highly toxic compound. The purpose of the present work was to obtain a general view about the acute effects of arsenic trioxide on liver metabolism using the isolated perfused rat liver, a system that preserves microcirculation and cell polarity. Hepatic lactate and alanine glu…