neuroimmunology

Nature Reviews Neuroscience, Published online: 30 April 2026; doi:10.1038/s41583-026-01046-0 Lung diseases drive substantial hospitalization, but available therapies remain limited. In this Review, Talbot and colleagues highlight pulmonary neuroimmunology — the bidirectional crosstalk between lung-innervating neurons and immune cells — and discuss how this axis may open new avenues for disease-mo…

Chronic pain is sustained by coupled neuronal hyperexcitability and neuroinflammation, yet prevailing frameworks incompletely explain why similar injuries diverge toward recovery or persistent sensitisation. Growing evidence indicates that lactate, succinate and itaconate act as signalling metabolites that shape glial state transitions and nociceptive circuit gain. Here, we synthesise preclinical…

Acupuncture has long been used to restore physiological balance, yet its biological basis has remained elusive. Recent research reveals that acupuncture operates through neuro-immune regulatory circuits rather than isolated local effects. Mechanical stimulation at acupoints is converted into neural electrical and biochemical signals, reshaping local immune microenvironments and triggering coordin…

A new study identifies an extreme but effective way that brain immune cells can prevent...

Dimitra Sokolova studies astrocytes, microglia and T cells from autism to Alzheimer’s disease Dimitra Sokolova arrived at the VIB-UAntwerp Center for Molecular Neurology (CMN) in October 2024 with a clear motivation: keep building on what she knows best—glial biology in Alzheimer’s disease—while also stepping into new territory. Just over a year later, that ambition is paying off. As a postdoctor…

BackgroundPuerarin is a flavonoid bioactive component extracted from the Chinese herb radix puerariae, which has been reported to have anti-inflammatory and neuroprotective effects and is a potential drug for the treatment of neuroinflammatory diseases. There is increasing evidence that the gut-liver-brain axis is closely related to neurological disorders. However, studies on the use of puerarin …

In recent years, breakthroughs in regenerative medicine have created new hope for families seeking alternatives to conventional autism treatment. At AMSA Biotech, our focus is on the development and application of biological therapies that not only address behavioral symptoms, but also target underlying neuroinflammatory and immune-related components often associated with autism spectrum disorder…

“Our neurogenetics legacy continues, but we’ve also made room for new directions” The VIB-UAntwerp Center for Molecular Neurology realigns along double axes of neurogenetics and neuroimmunology Under the joint leadership of Rosa Rademakers and Renzo Mancuso, the VIB-UAntwerp Center for Molecular Neurology is evolving. Long known for its pioneering work in neurogenetics, the center is now expandin…

Washington University School of Medicine in St. Louis has received a three-year $4.5 million grant from the Carol and Gene Ludwig Family Foundation, aimed at advancing research on neuroimmunology and neurodegeneration with the ultimate goal of developing new treatments for Alzheimer’s disease. Administered by WashU Medicine’s Brain Immunology & Glia (BIG) Center, the Carol and Gene […]

Harnessing this process may offer therapies for neuroinflammatory diseases such as MS, mouse study suggests

Written by Joao L. de Quevedo, MD, PhD Down Syndrome Regression Disorder (DSRD) is a perplexing condition that manifests as a significant loss of skills and abilities in individuals with Down syndrome (DS). While the exact mechanisms underlying DSRD remain elusive,... The post Neuroimmunology of Down Syndrome Regression Disorder appeared first on Louis A. Faillace, MD, Department of Psychiatry an…

Emanuela Pasciuto: making an impact in neuroimmunology An interview with VIB's newest group leader Emanuela Pasciuto starts her first lab of Neuroimmunology at the VIB-UAntwerp Center for Molecular Neurology in April 2023. I sat down with her in a cozy meeting room at the VIB-KU Leuven Center for Brain & Disease Research and interviewed her about her vision for it. Her enthusiasm is already palpa…