aging

Age-related molecular scores rose after emergency surgery, across pregnancy and during critical illness, then fell with recovery. The clocks are dynamic biomarkers, not proof that accumulated ageing was erased.

Nature Communications, Published online: 05 September 2026; doi:10.1038/s41467-026-77379-2 Osteoclasts need to manage reactive oxygen species by coordinating redox control and mitochondrial quality maintenance. Here, the authors identify OXR1 as a regulator of osteoclastogenesis and mitophagy, and show that genetic or pharmacological targeting of OXR1 attenuates bone loss in an osteoporosis mouse…

A sore knee can start as a small annoyance and gradually become a problem that changes how a person lives. For millions of adults, the cause is osteoarthritis, a common joint disease that can affect work, sleep, exercise and even emotional well-being. The knee carries much of the body’s weight whenever a person stands, walks […] The post Why Knee Arthritis Is Not Just an Aging Problem appeared fi…

Scientific Reports, Published online: 05 September 2026; doi:10.1038/s41598-026-69225-8 TNF-α and IFN-γ induce neurotoxicity in human iPSC-derived astrocytes that is enhanced by aging

Twisting movements are a part of everyday life. These exercises can help you do them with ease and control.

A surprising discovery suggests key warning signs may surface long before doctors can spot them.

Age-related shifts in the gut microbiome contribute to systemic decline, yet specific geroprotective pathways remain poorly understood. Analyzing human aging cohorts, researchers identified Bifidobacterium pseudocatenulatum as a key bacterium whose abundance declines sharply with age, correlating with advanced biological age via a novel microbiome aging clock. Mechanistically, the team traced thi…

Human longevity is one of medicine's oldest ambitions. Cureus invites you to put the field under the microscope, from senolytics and NAD+ to new cardiac and cancer procedures, and win Preferred Editing services for your future work. Submit by 16 October 2026.

We invite studies that uncover how cellular senescence contributes to ageing, including its molecular drivers, immune interactions, and tissue-specific dynamics.

Medicines Discovery Catapult provided its investment and expert support to help two biotech companies accelerate the development of new treatments for a range of autoimmune, inflammatory, and age-related diseases. The post Medicines Discovery Catapult Backs Two U.K. Biotech Companies Tackling Chronic Diseases appeared first on GEN - Genetic Engineering and Biotechnology News .

When the Stanford Center on Longevity launched in 2007, founding director Laura Carstensen spent a lot of time correcting misperceptions. “The initial response people had was, ‘Like the Methuselah Foundation? You are going to extend life?’” Carstensen was clear that the center’s aim was not to increase lifespans—which had nearly doubled during the 20th century—but rather to build societies that a…

Older female mice—equivalent in age to 60-year-old women—given daily injections of the active ingredient in Ozempic lived about 12 percent longer than animals that didn't receive the drug

People's bodies may reflect their ages very differently at the molecular level, even when they are the same chronological age, according to a new study.

The global aging demographic has precipitated a surge in late-life mental disorders (LMDs)—including late-life depression (LLD), anxiety, and behavioral and psychological symptoms of dementia (BPSD)—posing critical public health challenges. This review synthesizes current evidence on the unique pathophysiology, clinical management, and emerging frontiers of geriatric mental health, emphasizing th…

A substance found in edible sea squirts appeared to reverse several signs of aging in older mice. Plasmalogen supplements improved memory and learning, strengthened connections between brain cells, reduced inflammation, and even helped the mice grow thicker, darker hair. Researchers believe the compounds may encourage brain regeneration and protect aging synapses.

FRIDAY, Sept. 4, 2026 — There’s one personal factor that boosts survival among seniors who undergo surgery to repair a broken hip.Not how much money they have. Not where they live. Not whether they recuperated at home or in a nursing...

A new study in mice indicates that caffeinated coffee prevents stress-induced memory loss and depression-like behaviors, while decaf offers no such protection. The findings suggest caffeine is the key ingredient for coffee's mood-boosting benefits.