aging

Many people know that regular exercise is good for health, but there is often confusion about how much exercise is needed and which type provides the greatest benefit. Walking, running, cycling, and swimming are often recommended because they improve heart and lung health. However, another form of exercise is becoming increasingly important as people age: […] The post The Surprising Amount of Str…

Boston-based biotechnology company Life Biosciences has launched the first-in-human clinical trials of a pioneering “partial cellular reprogramming” technique designed to treat optic nerve damage caused by glaucoma and NAION. Based on previous genetic research, the therapy utilizes a modified virus to deliver three youth-restoring genes to retinal cells, aiming to reverse cellular aging while pre…

The first participant has been treated in a landmark clinical trial of cellular reprogramming, which aims to rejuvenate aging cells

As AI transforms biology, longevity startups are attracting investors, advancing toward clinical milestones, and reshaping the future of aging research.

Ok so, the parabiosis was a temporary effect, but the answer turned out to be having a blood transfusion with yourself instead. So if this video is right there is a molecule called HMGB1 which can be blocked rather than having said transfusion. Scientists may have identified one of the molecules that helps aging spread […]

Testosterone treatment may improve body composition, glucose metabolism and sexual desire in some older men at high risk of type 2 diabetes (T2D), but the benefits require engagement in a lifestyle program, according to a study being presented Saturday at ENDO 2026, the Endocrine Society's annual meeting in Chicago, Ill.

Spending more than an hour and a half in the sun each day could raise your chances of developing depression, dementia and dying early, according to new research. The findings, published in the journal Public Health, challenge the conventional wisdom sunny weather invariably boosts wellbeing. Scientists have long understood excessive sun exposure increases skin cancer risk. However, this study mar…

For decades, researchers have searched for ways to slow the biological processes that contribute to aging. While healthy habits such as exercise, nutritious diets, and good sleep remain the foundation of healthy aging, scientists are increasingly exploring whether certain medications might also help. A new study suggests that semaglutide, a drug already famous for treating […] The post Why This D…

Inadequate daily intake of this vitamin-like compound can lead to an enlarged heart, liver damage, weight gain as well as Alzheimer’s disease.

Just 90–120 minutes of strength training a week may deliver some of the biggest long-term health rewards, according to a study tracking more than 147,000 people for 30 years. That amount was linked to lower risks of death overall, particularly from cardiovascular and neurological diseases. Combining strength workouts with aerobic exercise produced even stronger benefits.

Scientists found a concerning Alzheimer’s link involving glucosamine, a joint supplement used by millions. A widely used supplement marketed for joint pain relief may be linked to faster progression of Alzheimer’s disease, according to new research from University of Florida scientists. The study found that people with mild cognitive impairment (MCI) who reported taking glucosamine [...]

The first participant has been treated in a landmark clinical trial of cellular reprogramming, which aims to rejuvenate aging cells

The human heart is one of the hardest-working organs in the body. It never takes a day off and requires a continuous supply of energy to keep beating. To meet these enormous energy demands, heart cells mainly rely on fats as fuel. For decades, researchers have viewed this ability to burn fat as a sign […] The post Disrupted metabolism linked to heart failure appeared first on Knowridge Science Re…

Millions of people take glucosamine every day in the hope of reducing joint pain and maintaining mobility as they age. The supplement has long been marketed as a natural way to support joint health, particularly for people with osteoarthritis. Because it is sold over the counter and does not require a prescription, many consumers assume […] The post Could a Popular Joint Supplement Increase Alzhe…

Inherited genetic mutations may also stay silent for decades before increasing the risk of diseases such as cancer or fibrosis later in life. Evolutionary Biology and Aging Research The researchers say their model builds on long-standing evolutionary theories of aging. One influential idea is that natural selection becomes weaker later in life, allowing harmful biological […]

A popular over-the-counter supplement taken for joint pain might increase people’s risk for Alzheimer’s disease, a new study says. Glucosamine use is associated with a 25% higher odds that a person will progress from mild cognitive impairment to dementia and Alzheimer’s disease, researchers report in the journal Nature Metabolism. “While it’s an association and not […]

Through spatial multiomics, spatial stable isotope tracing and retrospective cohort analyses, this study identifies hyperglycosylation as a driver of Alzheimer’s disease and a promising therapeutic target.

People with Alzheimer’s disease who took the common supplement glucosamine were 25% more likely to die within five years than those who didn’t. That’s the key finding of a new study that my colleagues and I published in the journal Nature Metabolism. Glucosamine is a sugar molecule that’s sold over the counter as a remedy […]

McMaster University is poised to become a global leader in kinesiology and healthspan optimization, thanks to a transformative $50‑million gift from alumna Dr. Marcy McCall MacBain, BSc '00, LLD '24 and John McCall MacBain, with the McCall MacBain Foundation. It is the largest philanthropic investment in kinesiology in Canadian university history.

Somewhere in a methylation dataset sits a child of ten whose body is already running fast. Not sick, not visibly different from the kid at the next desk, but ticking along at a pace that a particular kind of molecular clock can read off the chemistry of their DNA. The child grew up with less: less money, fewer resources, more of the low-grade stress that comes with scarcity. And that, it turns ou…