Joint trajectories of objective physical function and cognition and risk of incident dementia: a population-based cohort study

Lin Zhou
BackgroundThis study aimed to identify joint longitudinal trajectories of physio-cognitive aging, determine the temporal precedence between physical and cognitive decline, and evaluate both the mediating role of life space constriction and the moderating effect of sensory impairment on incident dementia risk.MethodsUsing 8-year longitudinal data from the National Health and Aging Trends Study (NHATS), we applied Parallel-Process Latent Class Growth Analysis (LCGA) to identify joint functional tr