Frontiers in Psychiatry | New and Recent Articles

IntroductionLimited research has examined participant subgroups enrolled in postpartum depression interventions. Via a cluster-randomized trial of the Mothers and Babies (MB) postpartum depression preventive intervention, we examined changes in depressive symptoms across pre-specified participant subgroups: race/ethnicity, first-time mother, language of intervention receipt, and client education.…

IntroductionDepression is a significant global health burden, with low- and middle-income countries disproportionately affected due to stigma, limited mental health resources, and imprecise diagnosis and treatment. In Latin America, reliance on non-specialized care further contributes to heterogeneous clinical outcomes. Although personalized medicine offers opportunities to improve depression man…

BackgroundAutistic youth are at elevated suicide risk, yet they face multiple barriers to mental health care, including a lack of interventions adapted to their unique needs and lived experiences. In the general population, brief interventions have been shown to reduce suicide risk during the high-risk period immediately following discharge from acute care for a suicide attempt. However, no suici…

BackgroundCaregivers of individuals with severe mental disorders often face a dual burden of affiliate stigma and reduced health-related quality of life (HRQoL). However, local evidence regarding the current status of these challenges and their interrelationship remains limited.MethodsThis cross - sectional study examined the level of affiliate stigma and its association with HRQoL among primary …

Recovery-oriented social psychiatry and psychiatric rehabilitation increasingly emphasize rights, participation, community-based care, supported decision-making, supported employment, and prevention-oriented early intervention. Yet formal access to services, information, rehabilitation, legal-administrative procedures, or participation formats does not by itself ensure that people can use these r…

Background and HypothesisSchizophrenia affects approximately 1% of the global population, with early diagnosis critical for optimal treatment outcomes. Resting-state quantitative electroencephalography (qEEG) represents a promising, non-invasive biomarker. We hypothesized that 18 years after the seminal Boutros review, advances in qEEG methodology would demonstrate characteristic neurophysiologic…

BackgroundAberrant interhemispheric functional connectivity has been implicated in the pathophysiology of schizophrenia. Voxel-mirrored homotopic connectivity (VMHC) provides a reliable measure of interhemispheric synchronization, yet the frequency-specific characteristics of VMHC alterations in schizophrenia remain poorly understood.MethodsResting-state functional magnetic resonance imaging data…

IntroductionMost of the research on reducing loneliness has taken a deficit-based approach that focuses on formal interventions rather than an asset-based approach that empowers individuals to manage their own loneliness. There is little understanding of the self-initiated strategies individuals use to manage their loneliness, and a lack of clarity on how perceived effectiveness and use of those …

ObjectiveTo systematically evaluate and compare the differences in treatment outcomes between open and closed psychiatric wards for hospitalized patients with depression, and to provide evidence-based support for optimizing psychiatric ward management models.MethodsPubMed, Web of Science, China National Knowledge Infrastructure (CNKI), Wanfang Data, and VIP Database were searched for relevant lit…

IntroductionProblematic social media use (PSMU) has become a growing research topic due to its potential psychological and cognitive consequences. However, little research has examined its relationship with everyday memory functioning, particularly specific forms of memory.MethodsA sample of 943 Spanish young adults aged 18 -35 completed validated measures of PSMU, everyday memory failures, prosp…

ObjectiveThis study aimed to examine the mediating role of Internet Addiction in the association between bullying victimization and Depressive Symptoms among left-behind children, as well as the moderating role of physical activity in this relationship.MethodsA cross-sectional design was adopted. A total of 21,689 left-behind children were recruited using stratified random sampling. A moderated m…

BackgroundGenetic factors can influence variation in cardiac structure. Schizophrenia (SCZ) is also highly heritable. However, whether cardiac structural variation is related to SCZ risk remains unclear and insufficiently examined from a "heart-to-brain" perspective.MethodsUsing data from 38,206 UK Biobank (UKB) participants, we assessed associations between 16 cardiac magnetic resonance imaging-…

The ongoing Russian-Ukrainian war has triggered a significant refugee crisis, resulting in widespread trauma, displacement, and mental health challenges among affected populations. This study aimed to explore the potential usefulness of logotherapy, a meaning-centered therapy, in addressing the mental health needs of Ukrainian refugees. The research was conducted in a naturalistic scenario of a g…

Jaak Panksepp spent nearly five decades mapping the primary-process affective systems of the mammalian brain across different species, producing a framework of considerable empirical power that is functionally invisible within psychiatry. Psychiatry has not built upon that literature in human contexts. Consequently, Affect has never occupied the foundational place in psychiatry that the evidence …

ObjectiveThis study examined the complex relationships among insomnia, anxiety, frailty, and cognitive function in middle-aged and older adults, testing whether frailty moderates the mediating role of anxiety between insomnia and cognition.MethodsThis cross-sectional study included 108 insomnia patients recruited from community and hospital settings between August 2025 and February 2026. Assessme…

BackgroundPosttraumatic stress disorder (PTSD) is associated with impaired sexual functioning in women, but the effects of complex PTSD (CPTSD) remain unclear. This study tested three hypotheses: (1) women with CPTSD would report lower overall sexual function than women with PTSD and trauma-exposed controls; (2) the pain domain would show the largest group differences; and (3) CPTSD symptom sever…

BackgroundHIV patients endure psychological distress throughout the phases of diagnosis, treatment, and rehabilitation, which considerably affects their quality of life. A thorough comprehension of patients’ psychological distress experiences is crucial for healthcare workers to devise focused solutions for enhanced care. This study aims to consolidate evidence concerning psychological distress i…

BackgroundChildren and adolescents undergoing treatment for malignant bone tumors frequently experience heightened psychological distress, including anxiety, depression, and reduced health-related quality of life (HRQoL). Group painting therapy has been proposed as a supportive non-pharmacological strategy, yet empirical evidence in pediatric oncology remains limited. This study aimed to evaluate…

BackgroundPostvention —structured support for individuals and communities exposed to or bereaved by suicide– is increasingly recognized as a core component of suicide prevention; yet standardized protocols and training frameworks remain scarce, particularly in low- and middle-income countries, leaving healthcare professionals without adequate guidance to respond effectively.ObjectiveTo identify a…

IntroductionConduct disorders are characterized by emotional dysregulation. Both callous-unemotional traits and social anxiety are heightened in conduct disorder patients and are associated with different mechanisms of emotion regulation. Previous evidence has proposed that secondary emotions, such as shame, might also be affected in conduct disorder and that callous-unemotional traits and social…