Frontiers in Microbiology | New and Recent Articles

Lagotis brevituba Maxim. (Lagotis brevituba), belonging to the genus Lagotis within the family Scrophulariaceae. The content of its secondary metabolites exhibits significant variation across different provenances, yet the underlying mechanisms linking these variations to microbial associations remain unclear. In this study, 12 samples of rhizosphere soil, root systems, and plant specimens of Lag…

Erwinia persicina (Ep) is recognized as an emerging pathogen of considerable threat to tomato yields. Although Stenotrophomonas rhizophila (Sr) has long been recognized as a plant growth-promoting rhizobacterium (PGPR), the use of this PGPR has sometimes been constrained by the rhizosphere stress factor in the biocontrol of the pathogen. This study investigated the potential of biogenic gold nano…

BackgroundEuschistus heros and Piezodorus guildinii are major soybean pests across the Americas. Gut-associated bacteria influence insect nutrition, detoxification, and stress tolerance, potentially enhancing adaptation to diverse hosts and management regimes. We investigated how host genetics and environment shape gut microbiome structure and functional potential in these species.ResultsWe seque…

Gut and skin microbiota impact host physiology and can be influenced by environmental changes, however, their reactions to rising environmental temperatures remain unclear. In this study, Bufo gargarizans tadpoles were exposed to 22 °C (control) and 27 °C (high-temperature) and the gut and skin microbiota were sampled at 24, 72, and 144 h to assess the effects of short-term elevated temperatures.…

Duck adenovirus 3 (DAdV-3) was firstly identified in Muscovy ducklings exhibiting slight pericardial effusion, swelling, and hemorrhaging in the kidneys, which is a poorly characterized duck virus. This study established a CRISPR/Cas12a coupled with a Lateral flow dipstick (RAA-CRISPR/Cas12a-LFD) detection platform for DAdV-3. The core mechanism of this platform involves a three-step cascade reac…

IntroductionAxillary bromhidrosis is characterized by excessive sweat gland activity and foul body odor, significantly affecting patients’ psychological well-being and social interactions.MethodsThis study recruited 30 axillary bromhidrosis patients and 30 healthy controls, collecting sweat and stool samples for microbiome analysis. Among the patients, 8 patients received microwave therapy, colle…

The rising concern of antimicrobial resistance, coupled with the continually challenging management of complicated diseases such as cancer, has provided momentum toward precision molecular medicine. This review provides an overview of bacteriophage enabled strategies encompassing both conventional antibacterial applications and advanced bioengineered delivery systems. Recent advances in phage the…

Protected cultivation systems offer opportunities for improving potato productivity but are often constrained by inefficient maize stover utilization and suboptimal fertilization practices. In this study, a 4 × 4 factorial experiment was conducted using the potato cultivar ‘Jishu No. 1’ to decode the rhizosphere microbial mechanisms underpinning plant growth and yield enhancement under greenhouse…

Escherichia coli enteritis causes substantial economic losses in animal husbandry, while antibiotic treatments face challenges of resistance and residue. This study investigated earthworm hydrolysate (EH) as a potential antibiotic alternative. In vitro assays demonstrated potent antibacterial activity of EH against E. coli, with an inhibition zone diameter of 12.24 ± 0.45 mm, a minimum inhibitory…

IntroductionThe rhizosphere microbiome serves as a critical line of defense for plant health and soil-borne disease suppression. However, the underlying mechanisms by which root-knot nematodes (RKN), a devastating soil-borne pathogen, undermine putative disease-suppressive function through destabilizing microbial interaction networks remain poorly understood.MethodsThis study employed metagenomic…

Recent research into decomposition has shed light on the intricate interplay within multi-kingdom communities, with microbial populations emerging as key players in the breakdown process and emphasizing their interactions within the broader decomposer ecosystem. Despite this, the specific roles and regulatory mechanisms of microbial communities remain underexplored. Gaining deeper insight into th…

IntroductionMycoplasma synoviae (M. synoviae) is an economically significant pathogen that causes respiratory infections, synovitis, and arthritis in chickens, inflicting substantial economic losses on the global poultry industry. Its frequent co-infection with other respiratory pathogens, often exacerbates the resultant pathogenic damage. As an important respiratory pathogen, it remains unclear …

Hyperuricemia is a metabolic disorder caused by excessive uric acid production or reduced uric acid excretion in the body. Approximately 30% of the uric acid in the human body is excreted through the intestines. As a vital component of the intestine, the gut microbiota influences host uric acid levels through multiple mechanisms and pathways, including purine metabolism, short chain fatty acid pr…

Microbial contamination in animal feed undermines livestock safety and storage stability, driving a critical demand for potent natural preservatives. This study investigated the antimicrobial efficacy of Alquermold Natural Plus L (AMNL), a formulation combining citric acid and bioactive monoterpenes, within compound feed and ground corn matrices. AMNL, applied at a dosage of 0.5 L/ton, was evalua…

IntroductionSiderophores are secondary metabolites with high affinity and specificity for iron and play a crucial role in iron acquisition. Vibrio fluvialis, an emerging foodborne opportunistic pathogen of increasing concern, produces the catechol siderophore fluvibactin. Quorum sensing (QS) is a process of bacterial communication vital for many biological processes. To date, the genes responsibl…

IntroductionIt is reported that addition of tangerine peel extract (flavonoids) can significantly improve the quality and flavor of tobacco leaves during fermentation. Nobiletin, tangeretin and hesperidin are the predominant flavonoids present in tangerine peel. However, their effects on the fermentation process of cigar tobacco leaves (CTL) have not yet been elucidated.MethodsThree major tangeri…

The global rise of multidrug-resistant bacteria necessitates the development of new antimicrobials and faster diagnostic tools. Conventional antimicrobial susceptibility testing is slow, relying on culture-based methods that delay effective treatment, often with fatal consequences in severe infections. In this study, we evaluate flow cytometry as a rapid, culture-minimal method to assess bacteria…

IntroductionThe emergence of multidrug-resistant bacteria, particularly vancomycin-resistant enterococci (VRE), represents a critical threat to global public health. Therefore, the development of novel therapeutic strategies is urgently required. Antimicrobial peptides (AMPs) are promising candidates for combating these infections. Persulcatusin (IP), an AMP from the hard tick Ixodes persulcatus,…

This study compared the growth performance, rumen fermentation patterns, and microbial community structure between three-way crossbred (Poll Dorset × Southdown × Hu, TNH) and purebred Hu (HH) sheep. A total of 75 male lambs (HH: n = 35; TNH: n = 40) with comparable birth dates were selected. After a 56-day suckling period, all lambs underwent an 84-day standardized fattening protocol with a unifo…