neurology

A Nature Metabolism study identifies brain hyperglycosylation as a metabolic driver of Alzheimer’s disease, with increased N-glycan biosynthesis seen in human AD tissue and mouse models. Reducing glycosylation improved memory in AD mice, while glucosamine worsened memory deficits in 5xFAD mice and was associated with poorer outcomes in dementia patients.

For many years, scientists have searched for the causes of Alzheimer’s disease. Most attention has focused on abnormal protein deposits that build up inside the brain. These protein clumps are considered one of the main signs of the disease. However, a new study suggests that another process may also be involved, and it comes from […] The post Could Alzheimer’s Disease Start With Mutated Immune C…

Over the past few decades, HIV has changed from a deadly disease into a manageable long-term condition for many people. Modern treatments can suppress the virus so effectively that patients often live for many decades after diagnosis. As a result, researchers are increasingly focused on understanding the long-term health challenges that remain, including problems that […] The post Flu Drugs Show …

As people age, changes slowly build up inside their cells. Every day, our cells divide, repair damage, and respond to the environment around them. During these processes, small mistakes can appear in DNA. These mistakes, known as mutations, become more common over time. Most of them are harmless, but some can affect how cells behave. […] The post Surprising Cancer-Like Changes in the Brain May Dr…

Inadequate daily intake of this vitamin-like compound can lead to an enlarged heart, liver damage, weight gain as well as Alzheimer’s disease.

Bill Ritter, anchor on WABC since 2001, said he’s stepping down but will continue to report on the disease A longtime New York City television news anchor has announced his sudden retirement from the airwaves after revealing that he has the early signs of Alzheimer’s disease. Bill Ritter, a veteran of ABC New York station WABC, has presented the main evening news in New York since 2001 and become…

For many people who suffer from depression, the condition is not just about feeling down but also about a loss of motivation and difficulty finding pleasure in activities they used to enjoy. A new study conducted in Sweden shows that a medicine used to treat Parkinson’s disease can be used as an add-on therapy to […]

A popular over-the-counter supplement taken for joint pain might increase people’s risk for Alzheimer’s disease, a new study says. Glucosamine use is associated with a 25% higher odds that a person will progress from mild cognitive impairment to dementia and Alzheimer’s disease, researchers report in the journal Nature Metabolism. “While it’s an association and not […]

Through spatial multiomics, spatial stable isotope tracing and retrospective cohort analyses, this study identifies hyperglycosylation as a driver of Alzheimer’s disease and a promising therapeutic target.

Though protein clumps associated with Alzheimer’s and Parkinson’s were discovered more than a century ago, researchers remain largely unable to prevent them from forming or eliminate them from the brain. And though a variety of therapies have taken aim at tau tangles, beta-amyloid plaques and Lewy bodies, among other notorious aggregates, none have been very […]

People with Alzheimer’s disease who took the common supplement glucosamine were 25% more likely to die within five years than those who didn’t. That’s the key finding of a new study that my colleagues and I published in the journal Nature Metabolism. Glucosamine is a sugar molecule that’s sold over the counter as a remedy […]

Researchers from NYU Abu Dhabi, in collaboration with Cleveland Clinic Abu Dhabi, have developed a tiny, injectable medical device that introduces a new approach to treating chronic pain and movement disorders by controlling nerve activity without the need for surgery, batteries, or wires, offering a simpler and less invasive way to treat neurological conditions.

Traumatic brain injuries (TBI) - even mild concussions - may trigger a chain reaction in the brain that disrupts neuronal communication, long-term memory, and cognition, according to University of California, Riverside research investigating how the brain's immune system responds after injury.

Alzheimer’s disease is the most common cause of dementia, affecting millions of people worldwide. It gradually damages brain cells, leading to memory loss, confusion, difficulty with daily activities, and changes in thinking and behavior. As populations continue to age, the number of people living with Alzheimer’s is expected to rise sharply in the coming decades, […] The post Simple Blood Test C…

Dementia remains stubbornly resistant to treatment and devastating for millions of people worldwide. Scientists have...

Farrah Mateen, MD, PhD, chief of the Division of Multiple Sclerosis & Neuroimmunology and the Dr. Charles L. Mix Research Professor of Neurology, has been named director of the Center for Global Neurology, a center of the Robert J. Havey, MD Institute for Global Health (IGH). The post Mateen Appointed Director of New Center for Global Neurology appeared first on News Center .

Background A 27-year-old male with perinatal hypoxia presented with global developmental delay, progressive hearing loss, ataxia, dysarthria, and intellectual disability. Whole-exome sequencing revealed compound heterozygous ACAD9 variants: c.456del (p.Ile153Serfs*46) and c.869G > A (p.Gly290Glu). Brain MRI showed bilateral cerebellar atrophy and a prominent cisterna magna. OCT confirmed optic at…

IntroductionPeripheral nerve conduction parameters vary between individuals and may reflect differences in peripheral neurophysiological function. This exploratory observational study examined whether ulnar nerve conduction measures and reaction time were associated with academic indicators among male medical students. The study was designed to provide preliminary evidence regarding possible asso…

A drug strategy abandoned after causing tremors, seizures and death in animals has been revived with a redesign that makes the compound less “sticky” — allowing it to let go faster from its target in the spinal cord. In mice, the new version relieved neuropathic pain without the dangerous side effects that derailed earlier attempts, potentially opening a new path beyond opioids for chronic nerve …

Fewer than one in four people with stroke and fewer than one in seven people with traumatic brain injury receive inpatient rehabilitation care after being hospitalized, according to a study published on June 10, 2026, in Neurology Open Access, an official journal of the American Academy of Neurology.