diagnostics

IntroductionErosive immune-mediated polyarthritis (IMPA) carries a poor prognosis due to irreversible joint destruction and poor response to therapy. Monitoring response to therapy can be challenging as systemic markers like C-reactive protein (CRP) are nonspecific for underlying causes of inflammation and repeated joint fluid collection by arthrocentesis for cytological analysis is invasive. In …

Mycoplasma bovis is a significant bacterial pathogen involved in the Bovine Respiratory Disease (BRD) complex. While assessing localized mucosal immunity is vital for understanding host defenses against respiratory pathogens, there is a lack of validated diagnostic assays for detecting mucosal immunoglobulins. This study aimed to evaluate the diagnostic performance of a novel multiplex ELISA plat…

IntroductionHemolysis during storage compromises the quality of canine and feline packed red blood cell (pRBC) units by shortening unit shelf-life, reducing oxygen-carrying capacity, increasing the risk of non-immune-mediated hemolytic transfusion reactions, and necessitating the discard of units when stock is limited.MethodsDonor- and unit-level determinants of percent hemolysis were investigate…

Awareness of disorders such as hypermobile Ehlers-Danlos syndrome is low among British healthcare professionals People in the UK with hypermobility conditions are waiting up to 21 years to be diagnosed while suffering from symptoms ranging from chronic pain to partially dislocated joints, research suggests. The study of more than 2,000 people, which was led by the University of Edinburgh and desc…

Every day, across thousands of American hospitals, artificial intelligence quietly shapes decisions that determine patient outcomes. An algorithm flags a patient as high risk for sepsis; a risk score informs whether a woman receives additional cancer screening; a deterioration model triggers an alert that sends a care team to a bedside. These tools are embedded […]

A new test provides a much more complete picture of DNA than current standard diagnostics and leads to a diagnosis more often. The test can replace 15 other tests, making it faster and more efficient. Researchers from Radboud university medical center recommend in the New England Journal of Medicine that this test be adopted everywhere […]

Many people think hearing loss happens very slowly and is simply an unavoidable part of growing older. Because the changes often happen gradually, it can be easy to miss the earliest warning signs. Someone may begin asking others to repeat themselves more often, struggle to follow conversations in busy restaurants, or find it harder to […] The post That Ringing in Your Ears May Be an Early Warnin…

Imagine wearing a small patch on your chest that quietly listens to your heart and lungs throughout the day. Instead of waiting for a doctor’s appointment, the device could continuously collect information about your health while you work, walk, eat, sleep, or relax at home. That vision may be closer to reality thanks to a […] The post A Bandage-Sized Device Could Let Doctors Listen to Your Heart…

For many people, high blood pressure can be managed with medications, healthy food choices, regular exercise, and weight control. But for a significant group of patients, these measures are not enough. Their blood pressure remains dangerously high despite taking several medications. Doctors call this resistant hypertension, and it is one of the most difficult forms […] The post Tiny Electrical Pu…

A new soft ultrasound patch is designed to provide long-term, hands-free monitoring of fetal health in real time. Engineers at the University of California, San Diego, have developed a soft, wearable ultrasound patch that can continuously monitor a fetus for hours at a time while maintaining reliable performance even as the fetus and umbilical cord [...]

Researchers identified distinct cellular neighborhoods in tumors that could be measured with a blood test to predict treatment response.

Prelude Corporation (PreludeDx(tm)), a leader in precision diagnostics for breast cancer, today highlighted a new milestone for DCISionRT(r), its validated genomic test that provides individualized recurrence risk assessment and predicts radiation therapy benefit for women diagnosed with ductal carcinoma in situ (DCIS).

Preliminary findings from a multicenter study are helping to answer a longstanding question in pediatric orthopedics: How reliable is computerized gait analysis interpretation across institutions?

The last time your blood pressure was measured, did you rush to the appointment while sipping coffee? Were you perched on an exam table with your legs dangling or your arm hanging? Were you chatting with a medical staff member or scrolling social media on your phone? Was your bladder full? Any of these actions […] The post The rules for measuring blood pressure – and why they exist appeared first…

Alzheimer’s disease is the most common cause of dementia, affecting millions of people worldwide. It gradually damages brain cells, leading to memory loss, confusion, difficulty with daily activities, and changes in thinking and behavior. As populations continue to age, the number of people living with Alzheimer’s is expected to rise sharply in the coming decades, […] The post Simple Blood Test C…

Technique that examines fragments of foetal DNA in mother’s bloodstream could limit need for invasive screening, according to researchers A new maternal blood test that can detect thousands of serious genetic conditions in the developing foetus could limit the need for invasive screening during pregnancy, according to scientists. The test, to be described at the European Society for Human Genetic…