pharmacology

Peppermint oil may have an unexpected benefit for people with mildly high blood pressure. Adults who took a small dose twice daily for 20 days saw their systolic blood pressure fall by an average of 8.5 mmHg, while a placebo group showed little change. Researchers say the inexpensive oil could eventually provide a simple additional option for managing elevated blood pressure.

The Food and Drug Administration granted Travere Therapeutics full approval for FILSPARI in focal segmental glomerulosclerosis on April 13, 2026, the drug’s second full approval after a 2023 clearance for IgA nephropathy. Travere’s stock rose 43 percent the next day, closing at $43.81.  The DUPLEX Data Behind a Second Approval FSGS damages the kidney’s filtering […]

A comprehensive analysis of nearly 1.6 million patients suggests that popular diabetes and obesity medications may increase the risk of a rare condition that causes sudden vision loss, though the absolute risk remains very low.

Nature Communications, Published online: 22 August 2026; doi:10.1038/s41467-026-76662-6 With the improvement of HER2-targeted therapy in patients with breast cancer, there is growing interest in whether chemotherapy can be eliminated from regimens completely. Here, the authors report a phase 2 clinical trial investigating neoadjuvant zanidatamab (HER2-targeting antibody) in patients with early-st…

Nature Communications, Published online: 22 August 2026; doi:10.1038/s41467-026-77068-0 A large international study found that certain diabetes drugs (GLP-1 receptor agonists) may link to a lower risk of tuberculosis than other common treatments. These medications may offer added protection against tuberculosis in type 2 diabetes.

A medicine cannot repair an arthritic joint if it disappears before it has enough time to work. That simple problem has limited efforts to develop better injections for osteoarthritis, especially for experimental drugs that dissolve poorly in joint fluid. A technology from the University at Buffalo aims to solve this by turning an injection into […] The post New Gel May Treat Arthritis More Effec…

A first-in-class therapy to target MYC, one of the most sought-after and difficult targets in cancer biology, showed promise in hard-to-treat blood cancers, according to a new preclinical study from The University of Texas MD Anderson Cancer Center published in Blood.

A study suggests that combining the two compounds with conventional treatment could reduce the need for antibiotics. For people with severe periodontitis, controlling the disease can require more than the standard removal of bacterial buildup beneath the gums. A study involving 109 patients found that adding omega-3 and low-dose acetylsalicylic acid (ASA) to conventional treatment [...]

U.S. poison centers have recorded a sharp long-term rise in liver injuries linked to medications and other foreign substances, with most severe enough to require inpatient care. Reports to U.S. poison centers involving liver damage from medications, supplements, alcohol, and other substances rose nearly 400% between 2000 and 2024, according to research from UVA Health. [...]

Anti-staphylococcal lytic agents, such as lysostaphin (LSN), a glycyl-glycyl (Gly-Gly) peptidase, have long been considered for the management of chronic and complicated bacterial infections typically resistant to conventional antibiotics, but their use is restricted by poor pharmacokinetic properties. We generated half-life extended lysostaphin constructs by fusing the lysin - either alone or ch…

Researchers at King’s College London have identified a surprising new therapeutic mechanism for a type of heart failure called heart failure with preserved ejection fraction (HFpEF), a condition that affects nearly half of all heart failure patients and has long resisted effective treatment. The post Natural Postbiotic Compound Shows Promise against Hard-to-Treat Heart Failure appeared first on S…

(BBC) – Some of the most prescribed medications, including those used to treat depression, ADHD and high blood pressure, can increase the risk of dehydration and other heat-related conditions. Many types of drugs used to treat mental health conditions, including … Read More

As we approach August 22, the FDA’s current Prescription Drug User Fee Act (PDUFA) action date for Capricor Therapeutics’ Biologics License Application (BLA) for Deramiocel, PPMD recognizes how closely the Duchenne community is watching for... The post Deramiocel: Where We Are Today appeared first on Parent Project Muscular Dystrophy .