Comparative efficacy of drugs with different mechanistic pathways/targets in the treatment of pediatric NAFLD: evidence from a Bayesian network meta-analysis
Yu-Qiang Liu
ObjectiveNon-alcoholic fatty liver disease (NAFLD) is now the leading cause of chronic liver disease in children and adolescents, and there is no defined treatment for this condition. A network meta-analysis (NMA) was conducted to examine the comparative efficacy of specific mechanism pathways of drugs to achieve improvements in hepatic steatosis in pediatric NAFLD patients.MethodsRandomized controlled trials regarding pharmacological interventions for pediatric NAFLD patients were obtained. Tre