Penfluridol directly targets PDPK1 to suppress AKT1 phosphorylation and stabilize CTR1, inducing cuproptosis in colorectal cancer
Chun-ze Zhang
Acta Pharmacologica Sinica, Published online: 25 May 2026; doi:10.1038/s41401-026-01806-9 Penfluridol directly targets PDPK1 to suppress AKT1 phosphorylation and stabilize CTR1, inducing cuproptosis in colorectal cancer