oncology

Scientific Reports, Published online: 16 June 2026; doi:10.1038/s41598-026-57367-8 Correction: Anticarcinogenic effects of miR-199a-loaded gold nanoparticles on hepatocellular carcinoma: in vitro study

New ACSM Expert Consensus Statement provides the first evidence-based exercise guidance for children and adolescents with cancer, finding that appropriately prescribed exercise is safe and can improve strength, physical function and recovery during and after treatment.

A human brain network associated with survival in children with diffuse midline glioma (DMG), the deadliest childhood brain cancer, has been identified by UCL clinician-scientists, raising the possibility of entirely new treatment approaches. The researchers found that DMG tumors seem to exploit the brain’s existing neural circuitry to drive tumor growth and progression. Tumors that […]

Induction chemotherapy for pediatric Acute Lymphoblastic Leukemia (ALL) is highly curative but accompanied by a severe toxicity profile. Evaluating the genetic susceptibility to these adverse events could inform hypothesis-generating risk stratification. In this exploratory retrospective cohort study (N = 178), we investigated the influence of 14 candidate pharmacogenetic variants on the developm…

Nature Communications, Published online: 16 June 2026; doi:10.1038/s41467-026-73467-5 The extracellular matrix provides structure to tumor tissue and can act as a barrier to anti-tumor immunity. Here, the authors demonstrate that enzymatic modification of matrix glycans shapes T cell-macrophage interactions and reduces immunosuppression within triple-negative breast cancer tumors.

Breakthrough treatment enabled Archie Goodburn, 24, to keep competing but he says one new drug in 20 years is not enough Archie Goodburn, a 24-year-old champion swimmer who has a rare, inoperable form of brain cancer, is calling for the government to do more to help people with the condition. “I grew up representing my country, and
I want to see my country supporting me back,” he said. Continue r…

There’s a small fatty gland that sits behind your sternum and is often said to be ‘useless’ in adulthood. Research, however, suggests the thymus gland is not nearly as expendable as experts once thought. Although not all scientists agree on this. In a study in 2023, US researchers found that those who get their thymus […]

BackgroundDemoralization is a common psychological distress in Chinese cancer patients, affecting treatment adherence and quality of life. NCCN Guidelines recommend routine monitoring of distress. The original 24-item Mandarin Demoralization Scale (DS-MV) is comprehensive but less suited for rapid, repeated screening in busy oncology clinics. We therefore refined and validated a short-form Mandar…

Wayne A. I. Frederick is a surgeon, scholar and university leader who has served as interim president of Howard University since 2025. He previously served as its 17th president from 2014 to 2023. A cancer surgeon and professor, his work focuses on health care disparities and medical education [This interview was edited for length and clarity.] How would you describe the current state of American…

Behind the Paper – by Tongji Xie, Lige Wu, Puyuan Xing, and colleagues. This blog is based on our paper “Mechanisms and Therapeutic Targets in Distant Metastasis of Lung Adenocarcinoma”, accepted for publication in Signal Transduction and Targeted Therapy.

CollimateHealth GmbH, a pioneering life sciences start-up for next-generation radiation therapy, announced the close of its €6 million seed financing round. The round was significantly oversubscribed and supported by renowned life sciences investors including VP Venture Partners, Positron, XISTA Sci...

This tip sheet from Sylvester Comprehensive Cancer Center, at the University of Miami Miller School of Medicine, features several cancer-related story ideas including paradoxical mesothelioma findings, a new immunotherapy drug for relapsed multiple myeloma, how gliomas evolve after treatment and more.

There's a small fatty gland that sits behind your sternum and is often said to...

Scientific Reports, Published online: 16 June 2026; doi:10.1038/s41598-026-58315-2 M²B-Net: a lightweight multi-scale multi-attention boundary-aware network for liver tumor segmentation from CT images

For many cancer patients, the most frightening part of the disease is not the original tumor but the possibility that cancer may return after treatment. Doctors can often remove tumors through surgery and destroy large numbers of cancer cells with chemotherapy or radiation. Yet even when scans appear clear, a small number of cancer cells […] The post Scientists Find a New Way to Stop Cancer Sprea…

Belzutifan, a first-in-class drug that arose from scientific discoveries at UT Southwestern Medical Center, has been approved by the Food and Drug Administration to treat some patients with earlier stage kidney cancers in combination with an immunotherapy drug.

Lonza and Antharis Therapeutics, Inc., a biopharmaceutical company developing next-generation antibody-based therapeutics for oncology, today announced an exclusive, target-specific licensing agreement to develop novel dual-payload ADCs targeting gastrointestinal (GI) cancers.

Nature Communications, Published online: 15 June 2026; doi:10.1038/s41467-026-74483-1 Responses to immune checkpoint inhibitors in patients with relapsed or refractory extranodal natural killer/T-cell lymphoma (R/R ENKTL) remain limited. Here the authors report the results of a phase 1b/2 trial of liposomal mitoxantrone plus anti-PD-1 tislelizumab in patients with R/R ENKTL.

Backgound: Prostate cancer (PC) incidence and mortality rates are significantly higher among Black/African-American (Black) men compared to men of other race/ethnicities. Comorbidities and compromised quality of life are also greater challenges for this community of men. Many factors drive these differences among which body composition and health behaviors are important, yet modifiable contributo…