vaccines

Nature Immunology, Published online: 25 May 2026; doi:10.1038/s41590-026-02522-6 mRNA-based vaccines saved millions of lives during the COVID-19 pandemic, but they require frequent boosting and periodic updates to match emerging virus strains. We demonstrate that fungal glycans can function as adjuvants for mRNA-based vaccines, expanding the durability and breath of protection against several vir…

Influenza A virus (IAV) continues to pose a substantial challenge to global health, not merely through primary viral pneumonia but largely due to lethal secondary bacterial complications. Pathogens such as Streptococcus pneumoniae, Staphylococcus aureus, and Haemophilus influenzae capitalize on the physiological “storm” induced by IAV, leading to significantly exacerbated morbidity. This review p…

A new review article is drawing attention to the growing global impact of human papillomavirus (HPV) and the rapid progress in vaccines and therapeutic strategies aimed at reducing the burden of cervical and non-cervical cancers.

The Bundibugyo ebolavirus outbreak continues to unfold against infrastructure and financing gaps and a broader system that struggles to respond to diseases of the poor and the peripheral

npj Vaccines, Published online: 23 May 2026; doi:10.1038/s41541-026-01494-w Heterologous vaccination with a next-generation vaccinia virus and Ad26 induces Ebola-specific immunity in macaques

A large new study has found that a vaccine designed to protect against respiratory syncytial virus, also known as RSV, may also help reduce the risk of serious heart and lung-related hospitalizations in older adults. The findings offer encouraging news for aging populations, especially for people already living with heart or lung conditions. The research […] The post This Vaccine May Help Older A…

Tuberculosis (TB) is one of the major public health challenges in Nigeria, especially in regions with poor healthcare resources. Chronic inflammation and immune function disruption is triggered by Mycobacterium tuberculosis (MTB), the causative agent of TB. This study was designed to assess Cytokine Profiles and changes in Hematological parameters in TB patients attending Mater Misericordiae Hosp…

npj Vaccines, Published online: 22 May 2026; doi:10.1038/s41541-026-01483-z Long-term cross-variant Fc-mediated immune responses against SARS-CoV-2 induced by a heterologous adenoviral/inactivated virus prime-boost vaccination strategy

npj Vaccines, Published online: 21 May 2026; doi:10.1038/s41541-026-01488-8 The role of naturally occurring and vaccine-induced Ad26 neutralizing antibodies in immunogenicity of Ad26-based vaccines

Abstract Purpose of Review The purpose of this review is to categorize and describe allergic and nonallergic causes, pathophysiology, subtypes, and treatment options for symptomatic nasal inflammation and rhinitis in general. Recent Findings Intranasal corticosteroids and antihistamines along with allergen immunotherapy are the standard of care for allergic rhinitis. While intranasal anticholiner…

Scientists and physicians should advocate to protect the vaccine research infrastructure that has saved an estimated 154 million lives over the past 50 years, according to a new commentary by researchers at Weill Cornell Medicine and the University of Washington.

In a new study published in Nature Immunology, researchers at Boston Children's Hospital demonstrated that pairing the original COVID-19 mRNA vaccine with an immune system enhancer, known as an adjuvant, extended the duration of the vaccine's protection in mice from a few months up to two years.

Tests with rodents suggest an mRNA vaccine in development offers protection against three strains of Ebola virus, including the one behind the current crisis

Nature, Published online: 22 May 2026; doi:10.1038/d41586-026-01660-z Nature staff discuss ongoing efforts to curb the Bundibugyo virus outbreak.

Nature Microbiology, Published online: 22 May 2026; doi:10.1038/s41564-026-02358-8 Vaccines have saved an estimated 154 million lives in 50 years, yet that infrastructure is under threat. We highlight the global impact of vaccine scientists who trained in the USA and urge for stronger communication, advocacy and public engagement to safeguard vaccine science.

Nature Immunology, Published online: 22 May 2026; doi:10.1038/s41590-026-02517-3 Jena, Qu et al. show that mannadjuvant, a formulation of fungal mannan and aluminum hydroxide, increases the magnitude, durability and breadth of the response elicited by mRNA-based vaccines against SARS-CoV-2 variants in mice and non-human primates.