IntroductionNatural products, especially polyphenol-rich medicinal plants, are increasingly investigated as multitarget therapeutics in both human and veterinary medicine for angiogenic regenerative properties and for inflammation based-diseases. Recent developments in natural product formulation, notably microencapsulation, have been shown to improve stability, bioavailability, and controlled release of bioactive compounds. The integration of complementary in vitro and in vivo models is critica