biochemistry

Nature Communications, Published online: 06 June 2026; doi:10.1038/s41467-026-73198-7 Human cystathionine beta-synthase (CBS) is shown to form distinct morpheein-style filamentous assemblies that regulate enzyme stability and activity in response to allosteric ligand binding, providing insights into CBS biology.

Solving humanity’s biggest problems has been OpenAI’s stated reason for pursuing artificial general intelligence since its 2015 founding, and over time, life science challenges have crystallized as core parts of its vision. In February 2025, CEO Sam Altman wrote that “we can now imagine a world where we cure all diseases,” and by that September… The post OpenAI research and product leads detail G…

Damage to DNA in cancer cells can lead to pieces breaking off chromosomes and floating away, like icebergs cracking off from a glacier. Scientists at Sanford Burnham Prebys Medical Discovery Institute and their colleagues published findings May 28, 2026, in Genome Medicine demonstrating significant similarities between samples of tumors featuring these stranded DNA fragments and research models d…

BackgroundThe incidence of bipolar disorder (BD) is an ongoing global public health concern, driving a heightened focus on elucidating its underlying pathophysiology. Mounting evidence indicates that epigenetic mechanisms play a pivotal role in the onset and progression of BD, presenting promising avenues for identifying novel biomarkers and therapeutic targets. However, a comprehensive bibliomet…

Nature Chemistry, Published online: 05 June 2026; doi:10.1038/s41557-026-02163-0 Proteins sharing a common fold can evolve strikingly different functions, but the underlying energetic logic is often hidden. Now, hydrogen exchange–mass spectrometry reveals conserved energetic ‘blueprints’ that distinguish Venus flytrap transcription factors from transport proteins, uncovering molecular switches fo…

Bio-Rad Laboratories, Inc., a leader in life science research and clinical diagnostics products, today announced that MicroVal, the international certification organization for the validation and approval of alternative methods for the microbiological analysis of food and beverages, has approved EZ-Check Listeria spp. and EZ-Check Listeria monocytogenes Kits for the detection of Listeria spp. and…

Agentic AI company Owkin and Sanofi have extended their collaboration with a five-year license for K Pro, Owkin’s AI scientist, under which Owkin will lead the end-to-end development of novel, purpose-built biopharma agents for Sanofi. Owkin pitches K Pro as a system that reasons over biological data and orchestrates AI agents to run research and… The post Sanofi deepens its Owkin bet with a five…

A gene normally responsible for repairing DNA may have a darker side when produced in excess. Cancer treatment is increasingly moving beyond where a tumor forms and focusing instead on the genetic flaws that drive it. Now, researchers at Penn State College of Medicine have identified an unexpected DNA repair gene that could help expand [...]

Scientific Data, Published online: 05 June 2026; doi:10.1038/s41597-026-07502-x An Integrated Dataset of Clinical and Microbial Profiles for Fecal Microbiota Transplantation

Nature Communications, Published online: 05 June 2026; doi:10.1038/s41467-026-74020-0 Monitoring structural changes in enzymes is essential for elucidating the mechanisms and dynamics of enzymatic catalysis, however, the transient conformational fluctuations involved in catalytic processes typically occur on microsecond-to-millisecond timescales, posing significant challenges for detection via co…

Ethnopharmacological RelevanceBunium persicum is a valued traditional Persian medicinal spice used as a calming and anxiolytic agent. However, the bioactive metabolites responsible for its antioxidant and anxiolytic effects, and their underlying mechanisms, remain largely unexplored.Aim of the StudyThis study evaluated the antioxidant and anxiolytic potential of hydroalcoholic extracts and solven…

Metabolic dysregulation is increasingly being recognized as a hallmark across various neurodegenerative diseases. While Alzheimer’s disease (AD) is well-established as a dual proteinopathy characterized by amyloid-beta (Aβ) deposition and tau protein tangles, the specific mechanisms mediating lipid homeostasis imbalance have garnered increasing attention. However, translating these findings into …

Northwestern Medicine scientists have developed a novel synthetic biomolecular condensate that can degrade intracellular disease-causing proteins, providing a framework for new therapeutic approaches for a wide range of diseases, as detailed in a recent study published in Nature Communications. Shana Kelley, Ph.D., the Neena B. Schwartz Professor of Chemistry, Biomedical Engineering, and Biochemi…

Nature Communications, Published online: 05 June 2026; doi:10.1038/s41467-026-74016-w Dual proteomics–lipidomics demonstrates that virus-induced lipid droplets rapidly recruit antiviral proteins and remodel lipids. These lipid–protein networks form signalling hubs, while specific long chain fatty acids enhance interferon responses and restrict viral replication.

At Indian Institute of Technology - Gandhinagar. The Development of Biosensors and Electrochemical Detection of Biomolecules