biochemistry

Radiochemistry and Radiopharmacy Solutions, more commonly known as RadCore, has launched an exciting new era of scientific possibility at Michigan State University, with several clinical trials underway fueled by the new central facility – the MSU Radiopharmacy. RadCore’s mission is to manufacture and transform raw radioisotopes into high-quality imaging and therapeutic agents for research studie…

Scientists at UC Riverside uncovered evidence that compounds beyond THC may influence how the body regulates metabolism and insulin signaling. A preclinical study from the University of California, Riverside offers new insight into a puzzling pattern that scientists have noticed for years: people who use cannabis chronically often have lower body weight and a lower [...]

Nonalcoholic fatty liver disease (NAFLD) is a prevalent metabolic disorder with a complex pathogenesis. Although epitranscriptomic modifications such as N6-methyladenosine (m6A) have been implicated in NAFLD, the role of N1-methyladenosine (m1A) and its regulators is largely unexplored.

Nature Communications, Published online: 25 May 2026; doi:10.1038/s41467-026-73711-y Cells prevent the mitochondrial Ca2+ uniporter from causing Ca2+ overload and cell death by expressing the non-conductive regulator MCUb. Here, the authors rebuild Ca2+ conductance in MCUb, revealing the molecular basis of its regulatory function.

BackgroundReflux esophagitis (RE), a common gastroesophageal reflux disease characterized by esophageal mucosal inflammation, is closely associated with gut microbiota dysbiosis and metabolic abnormalities. The glutamine-glutamate metabolic pathway regulates inflammation and mucosal barrier function, but its role in RE and association with gut microbiota remain unclear. This study aimed to charac…

Nature Communications, Published online: 25 May 2026; doi:10.1038/s41467-026-73658-0 Author Correction: Remote loop evolution reveals a complex biological function for chitinase enzymes beyond the active site

Diclofenac (DCF) is a widely consumed anti-inflammatory drug, frequently detected in aquatic environments worldwide due to the limited removal efficiency of conventional wastewater treatment processes. This work investigates the valorisation of brewery waste into functionalized carbon-based materials to mitigate the entry of DCF into aquatic systems. Biochar (BC) was produced from spent brewery g…

BackgroundPolystyrene nanoplastics (NPs) represent emerging environmental contaminants with potential adverse effects on salivary glands. This study investigated the protective effects of multi-strain probiotics against NPs-induced toxicity in rat parotid glands.MethodsForty male Sprague-Dawley rats were allocated into five groups (n = 8): control, NPs (10 mg/kg), probiotics (1010 CFU), NPs + pro…

A new scientific focus on extrachromosomal circular DNA (eccDNA) is opening transformative possibilities for disease detection, monitoring, and personalized medicine.

A new study suggests the gut microbiome may retain long-term signatures of past medication use, with some drugs leaving detectable effects years after treatment ends. Your gut may carry a record of medications you stopped taking years ago. A large study from the University of Tartu Institute of Genomics suggests that prescription drugs can leave [...]

Formally: Completing a PhD on the biophysical chemistry of nucleotides via molecular dynamics. Informally: A big fan of types, categories, and abstraction. Bad at algebra, but unwilling to quit trying. Having a grand time studying novel foundations of modern physics.

Scientists have identified new ways lithium chloride may interact with Alzheimer’s disease mechanisms at the cellular level. A new study from the University of Eastern Finland (UEF) suggests lithium chloride may influence several cellular processes linked to Alzheimer’s disease. Alzheimer’s disease (AD) is the most common type of dementia. One of its key features is [...]

Many disease-driving proteins sit outside cells, where they have been difficult to remove with conventional medicines. A new study shows how they can be linked to the cell’s own waste-disposal system and sent for degradation. That opens a new way to treat diseases in which the problem is not only what a protein does, but that it keeps being there.