organic-chemistry

Nature Communications, Published online: 22 August 2026; doi:10.1038/s41467-026-77053-7 Biomass derived α-, β-hydroxy acids can provide greener routes to valuable amino acids, but selective conversion remains difficult. This study shows isolated ruthenium sites can drive a new pathway from hydroxy acids to amino acids.

Nature Communications, Published online: 22 August 2026; doi:10.1038/s41467-026-76869-7 Reductive amination catalysed by imine reductases and reductive aminases is a powerful method for the asymmetric synthesis of chiral amines, yet the generality and practical limitations of these enzymes remain poorly understood. Here, the authors combine large-scale, iterative activity screening, sequence anal…

Professor Alexander T. Radosevich and Professor Alison Wendlandt have each been named 2026 Arthur C. Cope Scholars by the American Chemical Society (ACS). These awards are presented annually by the ACS to recognize and encourage excellence in organic chemistry. Radosevich, who joined the Department of Chemistry in 2016, was honored for discovering new reaction pathways […]

Nature Chemistry, Published online: 21 August 2026; doi:10.1038/s41557-026-02230-6 Bioorthogonal chemistry has greatly advanced our ability to explore and manipulate biological systems. Now, a genetically targeted photocatalytic strategy enables spatially controlled, non-natural organic transformations in specific cell types and subcellular compartments, combining abiotic reactivity with biologic…

Scientific Reports, Published online: 21 August 2026; doi:10.1038/s41598-026-67846-7 Linking molecular antioxidant activity to polyurethane foam stability - the case of Abies marocana essential oil

Deep-blue phosphorescent organic light-emitting diodes (Ph-OLEDs) are essential for advanced full-color displays, yet developing efficient and stable deep-blue emitters remains a formidable challenge. The post High-Efficiency and Stable Deep-Blue Iridium Phosphorescent OLEDs with Enhanced Charge Transfer Dynamics appeared first on Semiconductor Digest .

Nature Communications, Published online: 20 August 2026; doi:10.1038/s41467-026-76749-0 The authors report a ligand-controlled, regiodivergent palladium-catalyzed three-component Heck–Tsuji reaction of allenes, aryl iodides, and umpolung hydrazones. Leveraging the umpolung reactivity of hydrazones as sustainable carbanion surrogates enables the direct arylalkylation of allenes, forming two C–C bo…

Nature Communications, Published online: 20 August 2026; doi:10.1038/s41467-026-76384-9 Carboxylic acids are widely found moieties in feedstock chemicals as well as biomolecules, and as such, deuterations of scaffolds containing acid functionalities would be of synthetic use. Here the authors report a α-site-selective deuteration method that is compatible with both free amino acids and general (n…

Nature, Published online: 20 August 2026; doi:10.1038/s41586-026-11043-z Dialkyl ether synthesis through heteroatom homolytic substitution

dc.title: Asymmetric Ru-catalyzed carbonyl allylations via hydrogen transfer to π-unsaturated feedstocks : progress towards the synthesis of bafilomycin A₁ dc.description.abstract: Chemo-, regio-, and enantioselective C–C coupling of alcohols or aldehydes with unsaturated hydrocarbons to furnish chiral homoallylic alcohol products was achieved using iodide-bound ruthenium complexes that are stere…

IntroductionDevelopment of a mild and sustainable protocol for the carbon-carbon bond formation via Knoevenagel condensation is essentially desirable because the products, aryledene derivatives, are useful intermediates and are widely used in the manufacture of fine chemicals, pharmaceutically active molecules, calcium channel blockers, natural products, as well as in the production of flavours a…

Sodium Carbonate, and Ramenized Pasta Doing chemistry with baking soda, cabbage and an oven. Ramenizing things is super popular right now. The idea seems to have originated from the Ideas In Food crew, and is obviously adapted from the practice of making Ramen in Japan and similar alkaline noodles in China. In those recipes, the secret is incorporating an alkaline ingredient (such as kansui into …

The discovery has boosted the pharmaceutical industry and made research greener and cheaper.

Scientists have known about the ‘formose reaction’ for 160 years. New research shows how it could have played a key role in the creation of life.

Hemp-derived THC products are federally legal, for now. A chemist describes the different THC forms these products can contain and the legal restrictions placed on them.

A food chemist explains how black garlic is made, and how its health benefits are promising but still under-researched.

I vividly remember attending the 14th International Meeting on Organic Geochemistry in 1989 in Paris. I witnessed a presentation by John Hayes during which he introduced both a conceptual framework for interpretation of stable carbon isotopic compositions (?13C values) of biologically-derived compounds (biomarkers), as well as a novel analytical approach to measure ?13C values of individual compo…

Nature Communications, Published online: 19 August 2026; doi:10.1038/s41467-026-76813-9 γ-Tertiary-nitro-α-amino acids are valuable non-canonical amino acids that remain scarcely explored due to challenges in synthetic accessibility. Here, the authors report a pyridoxal-5′-phosphate (PLP)- dependent enzymatic platform that selectively couples O-acetyl-serine and secondary nitroalkanes to yield γ-…

Nature, Published online: 19 August 2026; doi:10.1038/s41586-026-10933-6 A one-pot skeletal-editing reaction replaces isoxazole oxygen with carbon to form challenging pyrroles, enabled by an N-propargylic enaminone intermediate and a computational model predicting reaction outcomes.