drug-delivery

A practical Journal of Controlled Release submission guide for drug-delivery researchers evaluating their work against the journal's mechanism and translational bar.

Bacterial infections, especially those involving drug-resistant pathogens and biofilms, pose a severe global health threat. Conventional antibiotic therapies are limited by poor penetration, low specificity, and bacterial resistance mechanisms. Magnetic nanoparticles (MNPs) offer a promising alternative by combining magnetically guided targeting, magnetothermal/photothermal effects, multifunction…

Nature Communications, Published online: 15 April 2026; doi:10.1038/s41467-026-71806-0 Author Correction: Fc-engineered large molecules targeting blood-brain barrier transferrin receptor and CD98hc have distinct central nervous system and peripheral biodistribution

The standard of care for proliferative retinopathies, such as diabetic retinopathy and age-related macular degeneration, has long relied on invasive intravitreal injections. These direct-to-eye needle procedures are often painful and carry risks of infection or increased ocular pressure. However, a scientific breakthrough published in April 2026 by researchers at Wayne State University and Washin…

Imagine a drug carrier you can watch as it moves, guide to a target, and then switch on at the right moment

The new company will advance targeted drug delivery in the brain with low-frequency focused ultrasound for blood-brain barrier opening.

Delivering therapeutic agents to the heart has long been a formidable challenge. While cardiovascular diseases remain the world’s leading cause of mortality, modern therapeutic strategies—including RNA medicines, protein drugs, and gene-editing tools—struggle to reach the myocardium in meaningful amounts. The heart’s unique structural and physiological barriers have historically limited the succe…

Abstract: The talk will explore the key challenges in the design and development of drug delivery systems aimed at targeted disease treatment. Special emphasis will be placed on strategies for crossing biological barriers, with a focus on targeting the brain, while also considering broader aspects of precision delivery, safety, and efficacy. The presentation will highlight current limitations, [&…

Neal Kassell, MD, writes about how focused ultrasound is being used to enhance drug delivery.

Key Points A recent paper highlights focused ultrasound’s flexibility as a platform for drug delivery to the brain. The publication, in the September 2024 edition of Nature Communications, demonstrated how focused ultrasound can be tuned to control the immune system’s response during blood-brain barrier (BBB) opening for therapeutic delivery. The researchers used advanced mathematical models and …

Lipid nanoparticles (LNPs) have emerged as one of modern medicine's most significant drug delivery systems.

For a long time, the poor solubility and low bioavailability of APIhave been a major problem for drug developers, and the low solubility has led to the limitation of its […]

Learn from and meet leading experts in pharmaceutical science, addressing the critical strategic advances and technical innovation in formulation, drug delivery, RNA therapeutics & inhaled therapies. The 2024 event will […]

Alzheimer’s disease (AD) is a very common neurodegenerative disease in old age, which not only affects the patient’s thinking, memory and independence, but also leads to a decline in the quality of […]

A company developing a drug delivery process with treatments activated by ultrasound received an option to license a key technology from its founders' university labs.

Liposomes, small spherical vesicles composed of lipid bilayers, encapsulate drugs, enhancing their stability and bioavailability.

Northwestern Medicine scientists have developed a wireless, self-powered, bioresorbable implant for programmed drug delivery, the details of which are published in PNAS. The post Self-Powered Wireless Implant Delivers Medication, Then Dissolves appeared first on News Center .

Treating cancer with combinations of drugs can be more effective than using a single drug. However, figuring out the optimal combination of drugs, and making sure that all of the drugs reach the right place, can be challenging. To help address those challenges, MIT chemists have designed a bottlebrush-shaped nanoparticle that can be loaded with […]

Biomedical Engineering & Biosciences - Juniper Publishers Abstract In recent decades the electrospinning technique has gained great interest in the scientific community. It is a simple and versatile technique that allows to obtain polymeric fibers at nanometric and micrometric scales. As a result of the process, two-dimensional and three-dimensional structures formed by fibers can be obtained…