Exploring the analgesic effect of artificial dura mater as a carrier for local hydromorphone delivery in posterior lumbar interbody fusion: a randomized controlled trial
Weibo Zhong
ObjectiveCarrier-based local hydromorphone delivery using absorbable materials represents an innovative strategy; however, comparative studies on various carriers remain scarce. This study aims to evaluate and compare the clinical efficacy of artificial dura mater versus gelatin sponge as carriers for hydromorphone in patients undergoing posterior lumbar interbody fusion (PLIF).MethodsThis single-center, prospective, randomized controlled trial was conducted at Ganzhou People’s Hospital, with pl