cardiology

Nature Medicine, Published online: 16 June 2026; doi:10.1038/d41591-026-00031-5 Engineered heart muscle allografts derived from induced pluripotent stem cells show promising early outcomes in patients with treatment-refractory advanced heart failure with reduced left ventricular ejection fraction, in support of further clinical investigation.

ObjectiveTo investigate whether Gastrodin (Gas) attenuates doxorubicin (Dox)-induced cardiomyocyte senescence and apoptosis by regulating the AMPK/mTOR/4EBP1 signaling pathway and autophagy-related processes.MethodsA Dox-induced senescence model was established in H9c2 cardiomyocytes, and different concentrations of Gas (0.5 mM and 1 mM) were used for intervention. Senescence phenotypes were eval…

Eric Topol is a cardiologist and scientist who is currently serving as the executive vice president of Scripps Research, the largest nonprofit biomedical research institute in the U.S. He is also founder and director of the Scripps Research Translational Institute. Topol has authored four best-selling books on the future of medicine and publishes Ground Truths, a weekly newsletter and podcast on …

BackgroundThe comparative cardiovascular effectiveness of different renin–angiotensin system (RAS) inhibitors in patients receiving maintenance hemodialysis remains uncertain, and current guideline recommendations largely assume therapeutic equivalence between angiotensin-converting enzyme inhibitors (ACEI) and angiotensin receptor blockers (ARB).MethodsUsing the TriNetX multi-institutional datab…

Researchers are warning that obesity is reshaping the global cardiovascular disease crisis, as trend data covering 204 countries reveal that heart disease now peaks in people aged 50-54 rather than the elderly and increasingly in South Asia, where rates have grown more than three times faster than global averages, according to a study being presented Monday at ENDO 2026, the Endocrine Society's a…

Synthetic cooling ingredients added to e-cigarettes caused abnormal heartbeats (arrhythmias) and increased cardiovascular risk measures in mice and lab-grown human heart cells, according to new independent research published today in Circulation: Arrhythmia and Electrophysiology, a peer-reviewed journal of the American Heart Association.

Nearly 7 million people in the United States are living with heart failure, and that number is expected to grow in the years ahead.

Most people think of heart disease and cancer as completely different illnesses. One affects the heart and blood vessels, while the other involves abnormal cell growth that can spread throughout the body. Yet researchers are increasingly discovering that the two conditions may be connected in ways that were not understood before. A new study led […] The post Hidden Heart Clues May Predict Cancer …

BackgroundHypertension-induced cardiac fibrosis leads to heart failure. Large-conductance calcium-activated potassium (BK) channels regulate vascular tone, and their activation may mitigate fibrosis. This study explores the impact of BK channel activation on angiotensin II (Ang II)-induced hypertension and cardiac fibrosis and its effects on nuclear factor-kappa B (NFκB) signaling.MethodsMale C57…

Bringing blood sugar levels back to normal may dramatically reduce the danger posed by prediabetes. Researchers found that people who reversed prediabetes cut their risk of cardiovascular death or hospitalization for heart failure by 58% and lowered their chances of major heart problems such as heart attacks and strokes by 42%. The benefits lasted for decades and were seen across large long-term …

Carbohydrates have become one of the most controversial topics in nutrition. For decades, diet trends have encouraged people to avoid foods such as bread, pasta, rice, and potatoes. Many popular weight-loss programs claim that reducing carbohydrates is the key to losing weight and improving overall health. As a result, low-carb and ketogenic diets have become […] The post Eating Some Carbs Could …

Healthy sleep and regular exercise can work to counteract genetic mutations in white blood cells that are associated with cardiovascular disease and are most common among older people, Mount Sinai researchers have found. In a study published in Nature, the team reported for the first time that sufficient sleep and exercise can help reduce the […]

Health experts are highlighting the importance of cardiac age, a measure that estimates the biological age of the heart based on factors such as blood pressure, cholesterol levels, smoking habits, diabetes, and lifestyle choices. Doctors warn that an individual’s cardiac Read More ... The post Your Heart May Be Older Than You, Doctors Caution first appeared on Risk Management Association of India…

The human heart is one of the hardest-working organs in the body. It never takes a day off and requires a continuous supply of energy to keep beating. To meet these enormous energy demands, heart cells mainly rely on fats as fuel. For decades, researchers have viewed this ability to burn fat as a sign […] The post Disrupted metabolism linked to heart failure appeared first on Knowridge Science Re…

Doctors have long treated heart disease and cancer as two separate health problems. Heart specialists focus on the cardiovascular system, while cancer specialists focus on tumors and abnormal cell growth. However, scientists are increasingly finding that these two major diseases may be more closely connected than previously believed. A new study led by researchers at […] The post Could Your Heart…

For many people, high blood pressure can be managed with medications, healthy food choices, regular exercise, and weight control. But for a significant group of patients, these measures are not enough. Their blood pressure remains dangerously high despite taking several medications. Doctors call this resistant hypertension, and it is one of the most difficult forms […] The post Tiny Electrical Pu…

A medical issue can send quotes for cover soaring but it is not worth risking going abroad without a policy “I nearly fell over when I saw the travel insurance quote,” says the retiree Bernie Lawrence. The 77-year-old from Fleet, Hampshire, says that after he developed heart problems, the cost of buying cover became “astronomical”. Lawrence, who usually travels with his wife, Barbara, 79, says he…

Scientific Reports, Published online: 13 June 2026; doi:10.1038/s41598-026-55974-z Path analysis of cardiovascular disease preventive health behavior in postmenopausal Korean women based on the I-Change model

For decades, pacemakers have helped millions of people live longer and healthier lives. These small devices are implanted inside the body and send electrical signals to the heart when its natural rhythm becomes too slow or irregular. Pacemakers are considered one of the most successful medical technologies ever developed. They have saved countless lives by […] The post MIT’s New Ultrasound Heart …