The impact of magnesium sulfate administration on outcomes in ICU patients with acute myocardial infarction: a retrospective cohort study

Rong Ding
BackgroundAlthough magnesium acts as a natural calcium antagonist with theoretical cardioprotective effects, its clinical value in critically ill patients with acute myocardial infarction (AMI) remains controversial. This study aimed to evaluate the impact of intravenous magnesium sulfate on ICU mortality in this population, and to explore potential dose-response relationships and effect modifiers.MethodsThis retrospective cohort study utilized the single-center Medical Information Mart for Inte