clinical-neuroscience

BackgroundTourette syndrome (TS) has traditionally been conceptualized as a movement disorder characterized by involuntary motor and vocal tics. However, growing evidence suggests that tic generation involves complex interactions between neural, physiological, and psychological processes, particularly the role of premonitory urges (PU).ObjectiveThis paper aims to develop an integrative model of t…

The vagus nerve connects the brain to major organs throughout the body and plays important roles in many bodily functions.

Radiochemistry and Radiopharmacy Solutions, more commonly known as RadCore, has launched an exciting new era of scientific possibility at Michigan State University, with several clinical trials underway fueled by the new central facility – the MSU Radiopharmacy. RadCore’s mission is to manufacture and transform raw radioisotopes into high-quality imaging and therapeutic agents for research studie…

Brain imaging reveals that young women who self-harm possess a distinct neurological vulnerability online. Unlike healthy peers, their brain's reward centers become highly engaged by negative comments, a trait that correlates with problematic social media use.

BackgroundLarge language models show promise in medical tasks, but their systematic error patterns in high-stakes clinical settings remain poorly understood, limiting safe deployment.MethodsA three-phase simulation study was conducted. In phase 1, researchers selected 103 multiple-choice questions and 30 clinical scenario questions, derived from an LBP examination question bank and clinical guide…

Nature Communications, Published online: 25 May 2026; doi:10.1038/s41467-026-73053-9 In drug-resistant temporal lobe epilepsy, thalamo–cortical synchrony in the first 20 seconds after seizure onset is stronger in clinical than electrographic seizures, highlighting network engagement as a key driver of seizure symptoms.

IntroductionFibromyalgia (FM) is a chronic pain disorder with unclear neuroanatomical basis, as previous studies largely relied on volumetric measures insensitive to cortical surface morphology. This multi-parametric surface-based morphometry study examined cortical thickness (CT), fractal dimension (FD), gyrification index (GI), and sulcal depth (SD) in FM.MethodsThirty-three female FM patients …

Scientific Reports, Published online: 25 May 2026; doi:10.1038/s41598-026-43151-1 Stabilizing fractional dynamical networks suppresses epileptic seizures

Introduction Neuropsychology teaches us that the brain is modular—different regions handle different functions. By studying what happens when these regions are damaged, we've learned more about how our minds work than almost any other method in psychology. Key Concepts Localization of Function : Specific brain regions are responsible for specific abilities (speech, memory, motor control, etc.) Le…

New research reveals that physical changes in the brain during adolescence, such as the expansion of the hippocampus, are closely linked to whether a child's ADHD symptoms will fade away, persist, or worsen over time.

Children and teenagers with a higher body mass index exhibit unique brain wave patterns that point to a reduction in neural inhibition. These neurological differences might make it harder for affected youths to alter ingrained dietary habits.

Benjamin Ellingson, PhD, and his team are developing advanced MRI and PET imaging techniques that allow clinicians and researchers to look beyond standard brain scans and study tumor biology and the tumor microenvironment in real time.

A "foundational" study found that the brains of children with ADHD matured later, but that finding was likely a mirage tied to issues with how the children were followed over time.

A new brain imaging study has found no evidence of widespread brain inflammation in patients suffering from prolonged symptoms after COVID-19 infection. Instead, the most severe long COVID symptoms were associated with increased brain activity in regions involved in mood and emotion.

Neuropsychopharmacology, Published online: 22 May 2026; doi:10.1038/s41386-026-02451-w Reconciling hippocampal semantic representations of traumatic memory in PTSD

Neuropsychopharmacology, Published online: 21 May 2026; doi:10.1038/s41386-026-02442-x Resting-state functional connectivity of the default mode network as a predictor for escitalopram response in adolescents with depression

IntroductionAmyotrophic lateral sclerosis (ALS) is a progressive motor neuron disease that leads to severe motor impairment, including loss of communication ability, and ultimately death. Communication brain computer interfaces (cBCIs) have the potential to restore communication without reliance on motor function, thereby improving quality of life, independence, and palliative care. However, stan…

IntroductionUnilateral cerebral palsy (UCP) results from early brain injury, leading to motor impairments primarily affecting one upper limb. Action Observation Therapy (AOT), which engages the mirror neuron system to enhance motor function, represents a promising rehabilitative approach. However, its efficacy in UCP has been inconsistent across studies, possibly due to methodological differences…

Living with PTSD can make everyday tasks feel overwhelming. A service dog trained specifically for PTSD can help you manage symptoms and regain independence in your daily life. To get a service dog for PTSD, you need to obtain a diagnosis from a mental health professional, connect with a reputable training organization, and either adopt ... Read more The post How to Get Service Dog for PTSD: A Si…