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A low-fat vegan diet may help people lose weight without counting calories, shrinking portions, or feeling constantly hungry. In a 16-week clinical trial, people eating mostly fruits, vegetables, grains, and legumes consumed about 357 fewer calories per day even though the total amount of food they ate barely changed.

Astronomers may finally have a clue to what happens to the mysterious “little red dots” that crowded the early universe. By studying a spiral galaxy nicknamed the “Saguaro,” researchers found a compact, bright red center that closely resembles these distant objects—but with something Webb usually can’t see around them: a full galaxy. When the team simulated what the Saguaro would look like much f…

Scientists are searching some of Earth’s oldest rocks for tiny fossils that could reveal how simple microbial life made the extraordinary leap toward plants, animals, and other complex organisms. Solving that ancient mystery may also help determine whether complex life could emerge on worlds beyond Earth.

Caltech scientists have created ultra-low-loss optical pathways on silicon chips that approach the efficiency of fiber optics and dramatically outperform existing technology at visible wavelengths. The breakthrough could unlock more powerful lasers, miniature atomic sensors and clocks, quantum systems, and more energy-efficient data centers.

Researchers have uncovered a surprising way triple-negative breast cancer may turn the body against itself. Tumors appear to recruit macrophages—immune cells normally involved in healing and fighting infection—and use them to release a protein called BDNF that draws nerves into the tumor. Those nerves may then help the cancer grow, resist treatment, and potentially spread.

A centuries-old heart drug costing less than ten cents a day could help keep heart-failure patients out of the hospital. New research suggests low-dose digoxin can reduce heart-failure hospitalizations by about 25%, potentially paving the way for its return as a major treatment.

Exercise and healthy blood sugar levels in midlife may help slow cognitive decline decades later. Physical activity appeared especially beneficial for Mexican American adults, suggesting that some brain-protective factors may differ across populations.

Aging gradually wears down the cartilage and fluid that protect our joints, but avoiding movement may actually make matters worse. Exercise helps nourish cartilage, strengthens the muscles that protect joints, and can reduce osteoarthritis pain. Low-impact activities such as swimming, cycling, tai chi, yoga, and walking on varied terrain may also improve balance and mobility. Even a few minutes o…

Physicists may have uncovered a hidden feature inside protons that helps preserve one of matter’s most fundamental properties. RHIC collision data suggest baryon number is carried not simply by three quarks, but by a Y-shaped junction of the gluons connecting them. The finding challenges a decades-old textbook picture and could deepen our understanding of why protons—and ultimately matter itself—…

As we age, the body appears to sacrifice walking efficiency in exchange for stability. Older adults stiffen the ankle more with each step, which may help prevent falls but also forces the muscles to work harder while producing less forward motion. This leads to shorter strides, slower walking, and faster fatigue. Exercises targeting balance, coordination, and lower-leg strength could help preserv…

Scientists have discovered a new extinct amphibian species hiding in the fossil collections of Los Angeles’ La Brea Tar Pits. Named Spea labreae, the Ice Age spadefoot toad is an exceptionally rare find—only one other extinct Pleistocene amphibian has ever been identified in North America. Its bones had been sitting in collections since the 1950s before a researcher noticed features that set it a…

Astronomers have witnessed a black hole violently shredding a massive star, creating one of the most energetic stellar explosions ever observed. The event, nicknamed “the Whippet,” briefly released about 400 billion times the Sun’s energy and sent a shock wave racing outward at one-fifth the speed of light. Months later, scientists spotted unexpectedly fast-moving helium, suggesting that some str…

COVID-19 can reactivate dormant viruses hiding in the body, including Epstein-Barr, cytomegalovirus, and several herpes viruses. One poorly understood viral family was strongly associated with long COVID and lasting disability, offering a potentially important clue to why some patients struggle to recover.

Rising carbon dioxide in the atmosphere may be leaving a measurable imprint inside the human body. Researchers analyzing more than two decades of U.S. health data found that blood bicarbonate levels have climbed about 7% since 1999, while calcium and phosphorus have declined—changes that closely track increasing atmospheric CO2.

Gut microbes need something to eat, and when fiber is limited, they may begin consuming proteins from the mucus lining that protects the gut. Researchers found that fiber can suppress this process, while indigestible plant proteins help microbes produce more beneficial compounds.

Fossils collected in Osaka more than 30 years ago have revealed a surprise hiding in plain sight: four previously unrecognized bones from a giant Cretaceous mosasaur. Among them is the first confirmed premaxilla—the frontmost bone of the upper jaw—ever identified in a Japanese mosasaur fossil. Even more intriguing, parts of the skull show unusual anatomical features that don’t match known mosasau…

A widely available food-preservation chemical is emerging as a disturbing factor in rising UK suicide deaths, particularly among younger people and men. Researchers say the scale may be underestimated and are calling for urgent restrictions on access and harmful online information.

Scientists have long thought an unusual genetic system helped ants, bees, and wasps evolve their extraordinary social colonies. A massive new analysis suggests that genetics alone can’t explain it—and the real secret may lie in other traits unique to these insects.

Scientists have uncovered why two seemingly opposite ways of targeting the same brain receptor can both promote weight loss. In mice, activating the GIP receptor in the brainstem reduced appetite, while blocking it in the hypothalamus removed a kind of “brake” on fullness signals. The discovery helps explain why very different obesity drugs can achieve similar results and suggests that carefully …

Scientists have discovered that the aging human brain may be far less isolated from the rest of the body than once believed. Stanford researchers found that large numbers of immune cells from the blood begin entering the brain as early as middle age, where they can transform into microglia, the brain’s specialized immune cells. The finding overturns a long-standing assumption that these cells rem…