Newswise Feature Channel: Biotech

Senescence is a state in which stressed cells stop dividing but remain alive. New findings reveal that the underlying process unfolds in distinct stages that depend on the type of drug used, and show how a new class of drugs triggers inflammation.

A new study from the Yale Department of Pathology and Department of Ophthalmology and Visual Sciences suggests that immune cells that live at the borders of the brain are shaped not only by inflammatory signals, but also by the physical environment of the tissues they inhabit.

One potential high-performance bio-based jet fuel is made from a chemical that is difficult to produce. However, biomanufacturing has the potential to make a precursor to this chemical, isoprenol. Researchers tested producing isoprenol in a type of yeast and found that the yeast is a possible host.

Thirty years ago, an insight from a rare brain disease took Robert Darnell's career in an unexpected direction. He's still surprised by what he's learning.

Scientists at Sanford Burnham Prebys Medical Discovery Institute, Mayo Clinic and their international collaborators published findings July 29, 2026, in Nature revealing a new connection between energy-producing mitochondria and chronic inflammation during aging. They also found that blocking a related gene reduced inflammation and promoted healthier aging in mice.

Researchers at the Icahn School of Medicine at Mount Sinai found that a chemotherapy-free combination of four targeted therapies showed encouraging results in patients with HR-positive, HER2-positive metastatic breast cancer, offering a potential first-line treatment option that may be more convenient for some patients and avoids chemotherapy.

Galvanize Therapeutics, Inc., a commercial-stage medical technology company pioneering pulsed electric field (PEF) therapies for oncology and chronic lung disease, today announced two new peer-reviewed publications that add to the growing body evidence suggesting Aliya PEF may do more than ablate tissue locally - it may also be immune system activating.

A team of Rowan researchers is turning collaborative research into a startup focused on helping bones heal faster and more effectively.

In a new study, scientists from Johns Hopkins Medicine report that an experimental mRNA-based platform has the potential to help deliver next-generation mRNA therapeutics, including vaccines fighting against infectious disease, cancer and autoimmune conditions, faster and more efficiently than the industry standard.

While a treatment that regrows lost limbs in humans remains many years away, the research of Wake Forest University's Josh Currie has brought the goal one step closer.

Researchers have developed a dopamine-enhanced soft electrode that helps wearable drug-delivery patches operate more reliably in wet conditions. The additive improves the electrode's structure, protects it during electrical operation and strengthens its attachment to the device. In laboratory tests using pig skin, the electrode delivered model compounds more effectively and remained functional du…

Artificial intelligence is reshaping one of drug discovery's most consequential questions: which compounds interact with which biological targets, and how strongly. A new review maps the fast-moving landscape of artificial intelligence (AI)-driven drug-target interaction (DTI) prediction, showing how the field has progressed from hand-crafted molecular features to deep learning, graph-based model…

Glycoprotein VI, or GPVI for short, is a surface receptor found exclusively on platelets and their precursor cells, megakaryocytes in the bone marrow. GPVI is primarily responsible for binding collagen at the site of an injured blood vessel, which triggers the activation and aggregation of platelets.

Desert sand is not suited for agriculture - but perhaps that might change. Researchers at Empa and Khalifa University in Abu Dhabi have investigated a first step in this direction by introducing microorganisms into the sand. The bacteria and fungi secrete biopolymers that make sand more resistant to erosion and slow down the rate at which water seeps through. This could potentially enable the gro…

Researchers at Karolinska Institutet and Stockholm University have developed a new tool that estimates a cell's biological age by analysing its gene activity. In the journal Advanced Science, they also demonstrate how the tool can be used to identify substances that influence cellular ageing.

Cancer patients often face more than the disease itself. Their treatment is frequently complicated by infections and other health conditions, meaning they may need to take several different medications at once. As the number of prescribed drugs increases, so does the risk of interactions between them, which is why scientists are searching for solutions that could one day address multiple problems…

In people with type 1 diabetes, the immune system mistakenly destroys the pancreatic beta cells responsible for producing insulin. Patients therefore require lifelong insulin therapy to regulate their blood glucose levels.

In a rare pair of papers published back-to-back in the journal Genes & Development, research teams led by senior author Anindya Bagchi, PhD, associate professor in the Cancer Genome and Epigenetics Program, establish a unified framework that governs one of cancer's most powerful master regulators.

Bacteria in lung tumors may boost the activation of innate immune cells in the presence of a common vitamin metabolite, according to a preclinical study by researchers from the Johns Hopkins Kimmel Cancer Center and its Bloomberg~Kimmel Institute for Cancer Immunotherapy.

The Wistar Institute announces the appointment of Brian Fuglestad, Ph.D., as associate professor in the Center for Advanced Therapeutics (CAT). Fuglestad uses biophysical and biochemical approaches to study proteins at the molecular and atomic level.