Newswise Feature Channel: Biotech

Sethera Therapeutics
2d ago

Karsten Eastman, CEO of Sethera Therapeutics, is available to discuss what the FDA's evolving approach to peptide medicines means for patients, consumers, investors, and the next generation of peptide therapeutics.

When cold strikes, plants face a dilemma: mount a full-scale defense that consumes precious energy, or risk fatal damage. Now, scientists have uncovered how a wild citrus species masterfully navigates this trade-off. They identified a small heat shock protein, CiHSP26.5, that is crucial for cold tolerance. More importantly, they discovered it is controlled by an antagonistic duo of transcription …

Polymethoxyflavones (PMFs), citrus-derived compounds valued for their diverse biological activities, remain difficult and expensive to manufacture because production still depends largely on plant extraction. The study identifies CsOMT5, a sweet-orange gene encoding caffeic acid O-methyltransferase 5, as a key controller of PMF formation and reveals an unexpected route beginning with the abundant…

Multidrug-resistant (MDR) pathogens and their antibiotic resistance genes (ARGs) in aquaculture tailwater pose serious risks to public health and food safety. Now, researchers have developed a bacteriophage-based disinfection technique that specifically targets and eliminates MDR Vibrio parahaemolyticus--a leading cause of seafood-borne gastroenteritis--along with the resistance genes it carries.…

Researchers have revealed the structure and composition of an understudied region called the transition zone in hair-like cilia. They show that mutations in two genes break linkers that hold the transition zone together, hampering the cilia's ability to clear mucus from the airways. The work adds to the number of genes known to cause the rare disease primary ciliary dyskinesia, which could help e…

Washington University in St. Louis
2d ago

The brain is a black box of densely packed neurons, blood vessels and immune cells, all locked away in a sealed skull. WashU's Song Hu has dedicated his career to unlocking that puzzle box by developing new ways to "see" inside. His team's newest innovation could give researchers a new view of how brain cells and blood vessels work together and what happens when the coupling between the two break…

Purple pak choi gets its striking color from anthocyanins--potent antioxidants that boost nutritional value. Yet the genetic switch behind this trait has remained elusive for decades. Now, researchers have assembled a near-complete genome of purple pak choi and uncovered an unexpected story: the key color gene, BraMYB114, did not originate in pak choi itself. It was borrowed from a distant relati…

research.ioresearch.io

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