bioinformatics

The human body and its gut microbiome produce thousands of small molecules that shape how the body functions—influencing immunity, metabolism and more. Identifying what those molecules actually are has been one of the biomedical sciences’ most persistent bottlenecks. More than 80% of compounds detected in a typical biological sample cannot be matched to any known […]

Why do two people with similar lifestyles sometimes have very different body weights and metabolic health? Food intake and physical activity are crucial, but they do not tell the whole story. New research involving more than 1 million people suggests that rare differences in DNA can give some individuals a powerful natural advantage in the […] The post A Million Genomes Reveal a Metabolic Advanta…

Are you pushing your body to the limit or just driving it into the ground? In the world of high-performance athletics and biohacking, Heart Rate Variability (HRV) has become the "North Star" for recovery. But raw numbers from your Garmin or Oura Ring only tell half the story. To truly understand the relationship between sleep quality , exercise load , and stress perception , we need more than a d…

Dark fermentation is the conversion of various biomass wastes into biohydrogen. It occurs in the absence of light. The purpose of this review is to provide the latest advances in biohydrogen production via dark fermentation, focusing on feedstock characteristics, microbial community dynamics, and approaches to system integration. Carbohydrate-based substrates are ideal for the production of biohy…

Background: Digital health applications generate rich behavioral data; yet, how users transition between behavioral states remains poorly understood. Existing approaches show limited capacity to capture and represent the evolving and nuanced nature of real-world behavioral dynamics, which are essential for informing personalized behavior change interventions. Objective: This study aimed to unders…

All known life on earth utilizes the same genetic alphabet, consisting of four letters. Now, researchers at University of California San Diego have demonstrated that one of biology's most essential enzymes can accurately read and transcribe an expanded, eight-letter genetic alphabet.

Scientific Reports, Published online: 04 September 2026; doi:10.1038/s41598-026-66916-0 Correction: GPU-accelerated modeling of biological regulatory networks

I built a tool that tells you if a DNA mutation causes disease. No cloud API. No paid service. Just a Python CLI on your laptop. Here's how it works — and how you can run it yourself. The Problem hen a single nucleotide changes in DNA (a missense mutation), it can alter a protein's function. Some changes cause disease. Most don't. ClinVar — the NIH's database of known variants — has ~2,800 classi…

Nature Communications, Published online: 04 September 2026; doi:10.1038/s41467-026-77407-1 Crosslinking mass spectrometry (XLMS) has become the method of choice for uncovering protein interactions and structure in vivo. Here, the authors present pyXLMS – a python package and web application – to streamline the down-stream analysis of XLMS results to extract biological meaning.

[Communications Biology] Researchers developed SWIFT, Single-organoid Workflow for quantitative Imaging classiFication and Tracking, a fast and modular pipeline for quantitative, time-resolved organoid analysis from brightfield images.

Nature Microbiology, Published online: 03 September 2026; doi:10.1038/s41564-026-02474-5 Integron insertion sites engineered into counterselection markers allow large-scale and high-throughput capture of integron-encoded genes from genetically tractable bacteria or DNA samples.

With artificial intelligence and careful modeling of fossilized wings, researchers reproduced how some extinct, katydid-like insects might have made noise

Are you a new transfer student interested in learning more about the diverse fields and opportunities within bioengineering? Join the Breaking Down Bioengineering DeCal! This course is designed to introduce students to various bioengineering topics, research areas, and career paths through guest lectures from professors and industry professionals. Our class meets on Tuesdays from 7:00…

The VIC lab has developed a tool called MIAAIM (Multi-omics Image Alignment and Analysis by Information Manifolds) that integrates multiple sources of imaging data to generate a more comprehensive view of human health and disease. By combining complementary imaging modalities, this modular framework may help identify patterns and biomarkers that are not visible through a […] The post VIC collabor…

Three of Seattle's top scientific institutions are launching a nearly $95 million research initiative that will generate data and train AI models to design proteins and genes that don't exist in nature — sharing the results freely to help others develop new medicines and materials. Read More