GEN – Genetic Engineering and Biotechnology News

Researchers kept human brain organoids developing for over five years, revealing prolonged maturation that mirrors human brain development and creating new opportunities to study disorders and test drugs. The post Five-Year Brain Organoids Reveal New Insights Into Human Development appeared first on GEN - Genetic Engineering and Biotechnology News .

Researchers developed a computational tool that could help to finding genes most directly related to disease, and which in a reported study identified 21 genes related to asthma, most of which hadn’t been discovered by other methods. The post DANDELION Computational Tool Identifies Previously Unknown Asthma-Related Genes and Pathway appeared first on GEN - Genetic Engineering and Biotechnology Ne…

By using chemical signals to guide cells to adopt distinct regional identities, scientists created lab-grown human organoids that mimic early brain development and could illuminate how specialized brain areas emerge. The post Lab-Grown Neocortex Models Mimic Early Brain Organization appeared first on GEN - Genetic Engineering and Biotechnology News .

A human multi-organ chip models how breast cancer spreads from blood vessels to bone and lung, offering a patient-specific tool to study metastasis and potential treatments. The post Human Multi-Organ Chip Offers New Insight Into Cancer Metastasis appeared first on GEN - Genetic Engineering and Biotechnology News .

Researchers studying immune cells in Japanese supercentenarians have found that normally rare, CD4 cytotoxic T lymphocytes become increasingly abundant with extreme age, and may help to stave off cancer. The post Rare Immune Cell Type in Supercentenarians May Help Maintain Healthy Aging appeared first on GEN - Genetic Engineering and Biotechnology News .

Advances in manufacturing, automation, and lentiviral vector technologies are reshaping the future of CAR T therapies. Ex vivo and in vivo approaches will evolve together, helping improve scalability, lower costs, and expand patient access worldwide. The post CAR T Manufacturing Innovation Expands Patient Access appeared first on GEN - Genetic Engineering and Biotechnology News .

Reusing spent culture media in an L. lactis cell fermentation model streamlines continuous bioprocessing and cuts costs for FGF2 production, making serum-free production increasingly cost-effective and productive. The post Cutting Costs in Serum-Free FGF2 Processing With Recycled Media appeared first on GEN - Genetic Engineering and Biotechnology News .

BlueRock says it’s helping advance the cell therapy industry by developing an automated system for analytical auditing. They say it’s among the few systems specifically designed for this application. The post Cell Therapy Company Aims to Pioneer Analytics Automation appeared first on GEN - Genetic Engineering and Biotechnology News .

More effective purification materials would make viral vector production more efficient, say researchers working on an affinity adsorbent-based method they claim can differentiate between full and empty capsids more effectively than current methods. The post Vector Production a Bottleneck for Gene Therapy Sector appeared first on GEN - Genetic Engineering and Biotechnology News .

DNA regulatory elements, which control when, where, and to what extent specific genes are turned on or off, can be co-opted by scientists to create gene switches. The post Gene Switch Uses Electromagnetic Fields to Control Genes Remotely appeared first on GEN - Genetic Engineering and Biotechnology News .

In this GEN webinar, experts from Rose BioSolutions, a CDMO and Cell Solutions organization formed from Charles River Laboratories’ businesses, will discuss how integrating regulatory strategy at the earliest stages of development can reduce overall risk and improve program outcomes. The post Embedding Regulatory Strategy in Cell and Gene Therapy Development appeared first on GEN - Genetic Engine…

Participants who consumed at least one serving of a sugar-sweetened beverage per day had a 2.45X higher risk of gastric cancer compared with those consuming less than one serving per month. The post Sugar-Sweetened Beverages Daily Can Lead to Higher Stomach Cancer Risk appeared first on GEN - Genetic Engineering and Biotechnology News .

Researchers discovered that a key molecule released during exercise strengthens muscles, improves exercise performance and could be a therapeutic treatment for muscle damage caused by type 2 diabetes. The post Exercise-Boosting Molecule May Help Improve Muscle Health in Type 2 Diabetes appeared first on GEN - Genetic Engineering and Biotechnology News .