endocrinology

Gestational diabetes mellitus (GDM) is a common, inflammatory complication during pregnancy. Women who have GDM are more likely to develop metabolic or cardiovascular disease in the years post-delivery, as are their children. The umbilical cord and placenta provide a unique interface between maternal and foetal circulation and are richly vascularised. However, the molecular and cellular mechanism…

Scientific Reports, Published online: 11 September 2026; doi:10.1038/s41598-026-71306-7 OCTA-based evaluation of retinal microvascular changes during recombinant GH therapy in children with GH deficiency

Aging may not impact your testosterone levels as much as you might think. From the...

Identifying distinctive types of conditions like diabetes is helpful in two ways. It means treatments can be personalized more precisely to individuals, and gives researchers a better idea of how to make those treatments more effective going forward. When it comes to type 1 diabetes, there are two genetic patterns called HLA-DR3 and HLA-DR4 that […]

A phase 3 trial is showing "a potentially giant step forward," in treating children with achondroplasia, UCLA Health's Dr. Isidro B. Salusky wrote in a new editorial published in the New England Journal of Medicine (NEJM).

Testosterone is often discussed as a hormone that affects sexual health, muscle strength, energy, and mood. But researchers are increasingly interested in how testosterone levels may also influence the heart, especially the risk of developing an abnormal heartbeat called atrial fibrillation. A new review published in the Journal of the Endocrine Society suggests that both […] The post Both Low an…

Scientific Reports, Published online: 03 September 2026; doi:10.1038/s41598-026-69769-9 Identification of RAB36 and NINL as potential diagnostic biomarkers for gestational diabetes mellitus and polycystic ovary syndrome

Patients with type 2 diabetes who have high blood glucose levels, low body weight, or a history of ketoacidosis are at increased risk of developing this serious condition when treated with so-called SGLT2 inhibitors.

Millions of people with high blood pressure may have an underlying hormone disorder that is never diagnosed. New research suggests a wearable device that measures hormones throughout the day and night could make this hidden condition much easier to detect. The condition is called primary aldosteronism. It happens when the adrenal glands produce too much […] The post Study Finds Hidden Cause of Hi…

Hot flashes, poor sleep and mood changes are familiar parts of menopause for many women, but there is no single menopause experience. Symptoms can be mild for one person and exhausting for another. New research suggests that type 2 diabetes and prediabetes may help explain some of these differences, particularly after menopause. A study of […] The post Blood Sugar Problems Linked to Tougher Menop…

[Diabetes] Scientists combined human islet single-cell transcriptomics with mouse pancreatic-cell profiling to show that pericytes, rather than endothelial cells, are the primary source of hepatocyte growth factor (HGF) in healthy islets.

[Diabetologia] The authors highlight recent discoveries in human pancreatic islet and β-cell biology, exploring how new models and technologies could advance strategies to restore insulin-producing cells in diabetes.

A study in mice found that male sex hormones can suppress allergic responses by promoting sympathetic nerve connections and norepinephrine release in the lungs. The post Male Sex Hormones Suppress Lung Allergies by Acting on Neurons in Mice appeared first on GEN - Genetic Engineering and Biotechnology News .

IntroductionPolycystic ovary syndrome (PCOS) is one of the most common endocrine and metabolic disorders affecting women of reproductive age. Dendrobium officinale polysaccharides (DOP) have shown multiple pharmacological activities, but their therapeutic effects and underlying mechanisms in PCOS remain incompletely understood.MethodsA dehydroepiandrosterone (DHEA)-induced mouse model of PCOS was…

In people with type 1 diabetes, the immune system mistakenly destroys the pancreatic beta cells responsible for producing insulin. Patients therefore require lifelong insulin therapy to regulate their blood glucose levels.

Higher habitual coffee intake was associated with a leaner body composition, lower circulating branched-chain amino acids, and distinct cardiometabolic patterns in 2,264 middle-aged Finnish adults. Hormonal associations differed by sex, with broader testosterone- and SHBG-related patterns in men and more limited SHBG-related changes in women.

Insulin is a cornerstone of treatment for patients with type 1 diabetes, essential for lowering blood glucose levels. However, if insulin doses are not appropriately matched to the body's needs, glucose levels can fall too low, resulting in hypoglycemia, a common and potentially dangerous complication of treatment. Hypoglycemia can impair thinking and cause symptoms ranging from dizziness and con…