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On January 10, 2024, a dim star in the constellation Gemini began to disappear. Not dramatically, not all at once, but gradually, its light thinning by degrees as something cold and dark slid in front of it. From three stations across Japan, astronomers watched the light curves on their monitors and saw what they hadn’t expected to see: a gradual fade where physics said there should be an abrupt …

astronomyplanetary-science

For any hospital chief executive watching the balance sheet erode, the pitch from a management consulting firm must be hard to resist. Here, the partners promise, are people who have seen every operational failure, every cost spiral, every revenue leak in the industry, people who can fix things (in a matter of months, they promise) what internal staff have struggled with for years. The consultant…

Every yellowtail snapper excretes ammonia. It cannot help doing so; it is a metabolic inevitability, the nitrogen-rich byproduct of a fish eating, breathing, living at commercial density in a tank on Virginia Key, Florida. In a conventional aquaculture operation, that ammonia accumulates in the effluent water until it becomes a problem, sometimes a serious one, for the marine environment downstre…

agricultureaquaculturebiologyenvironmentsustainable-farming

Sitting on the ocean floor, anchored to the continental slope of North America, a cluster of instruments has been recording something that nobody particularly wanted to see. Pressure sensors and current meters, deployed at depths where no light reaches, have logged the slow behavior of water moving in the dark for two decades. The data they’ve accumulated now points, with unusual consistency, to …

climate-scienceearth-scienceenvironmentoceanography

Every few minutes, a living cell does something quietly extraordinary: it sheds tiny membrane bubbles into the fluid around it. These extracellular vesicles carry molecular cargo (proteins, lipids, fragments of RNA) and cells have been doing this for so long that biologists spent decades trying to understand what the bubbles were for. A team at the Technical University of Munich has now turned th…

biochemistrybioinformaticsbiologycell-biology

One tenth of one percent. That is all it takes. Out of billions of parameters inside a large language model, only a tiny, specially chosen sliver, roughly 0.1%, carries the information that actually matters when the model needs to learn something new. The rest is, in a sense, dead weight during the update. Recognising this has led a team of researchers at Stevens Institute of Technology to an alg…

aicomputer-sciencemachine-learning

There’s a mineral called bustamentite that almost nobody studies. It forms in flat hexagonal plates, grows readily in warm water, and turns up as an unwanted contaminant in perovskite solar cells. For decades it sat at the margins of materials science, useful mostly as a precursor for more fashionable compounds. Then a group of physicists decided to look at it very carefully in the terahertz rang…

materialsnanomaterialsphysicssemiconductors

During meiosis, the process by which sperm are made, chromosomes must sort themselves with extraordinary precision. Each mature sperm cell is supposed to carry exactly 23 chromosomes: one sex chromosome, either X or Y, and 22 others. When the sorting goes wrong, a sperm ends up with an extra chromosome, sometimes two sex chromosomes instead of one, sometimes none at all. Most of the time this mat…

biologygenetics

Six dollars and fifty cents. That is, give or take, the largest fine the federal government has ever levied on a Medicare Advantage insurer per patient enrolled. It happened once, in 2019. Most years the figure stays below three dollars. Meanwhile the same insurers receive, on average, somewhere in the neighbourhood of $15,000 per enrollee annually from the federal government. Do the arithmetic a…

health-policymedicinepublic-health

Run an AI model across a human chromosome and what you get back looks like a seismograph readout: peaks and troughs, quiet stretches interrupted by jagged eruptions of ancient time. The quiet zones are where evolution swept through recently, pushing all the variants in a population toward a single common ancestor. The peaks are where something else happened, something older and stranger, where co…

aibioinformaticsbiologymachine-learning

Somewhere in the gap between a person deciding where to live and a nation’s wealth clustering in a handful of cities, something gets lost. Economists model the aggregate; sociologists study the individual; neither, quite, manages to speak the other’s language. The equations that govern a gas of molecules, however, turn out to say something rather precise about how both come to be, and a new paper…

behavioral-economicseconomicssocial-science

The numbers came back wrong. Researchers at the University of New Mexico had been methodically working through preserved brain tissue, running the usual analyses on samples drawn from a cohort of donors spanning 2016 to 2024. What they found was not a trace signal or a statistical whisper. The human brain, it turned out, carries microplastic concentrations seven to thirty times higher than matche…

biodiversitybiologyenvironmentpollution

Somewhere in the naming of animals, science and theology have always made uneasy company. The Old Testament hands Adam his first job: go through every creature and give it a name. Taxonomy, in other words, is possibly the oldest human profession. Peter Huemer, a moth researcher at the Tyrolean State Museum in Innsbruck, seems to reckon it’s also one of the most urgent. His newest contribution to …

biologyconservationtaxonomy

Spend a winter in Finnish Lapland and you quickly learn that lakes are not simply frozen. They are stratified, layered, chemically active places whose temperature at the bottom tells you something about the autumn that preceded them. Which makes a finding published in Water Resources Research this spring particularly unsettling: across roughly 50 years of monitoring data from dozens of Finnish la…

climate-scienceenvironmentwater-resources

At the centre of a water molecule, tucked inside its hydrogen atom, there is usually just a single proton. Nothing else. But in a small fraction of the water on Earth, and in comets and asteroids scattered throughout our solar system, that proton has a neutron companion, making the hydrogen heavier, turning H2O into something denser and slightly more sluggish: deuterated water, or HDO. The ratio …

astronomycosmologyplanetary-science

Iron ions drift into a freshly printed gel, soaking through its polymer mesh the way water moves into a sponge. Then the gel is dipped into a second bath, this one laced with hydroxide ions, and something clicks: the iron bonds, crystallizes, becomes magnetite, iron oxide nanoparticles forming in place, locked inside the structure, too small to see without an electron microscope. The gel, moments…

engineeringmaterialsnanomaterialspolymers

For eighteen years, radio telescopes have been staring at the same small patch of sky in the constellation Cygnus, watching a black hole do something that black holes do rather well: devour its companion star and fling what it can’t swallow back into the universe at half the speed of light. The watching has been patient, meticulous, and until very recently, frustrating. The jets blazing outward f…

astronomyastrophysicsgravitational-waves

Every time a clinician runs a probe across a pregnant abdomen, a remarkable act of physics plays out in the tip of that device. The material inside converts electricity into vibration so precisely that it can sketch a face before birth. These materials, called relaxor ferroelectrics, have powered ultrasound scanners, sonar systems, and microphones for decades. And yet, right up until last week, n…

condensed-matterphysicssurface-science

Oleic acid has a reputation to uphold. The primary fatty acid in olive oil, it sits at the heart of the Mediterranean diet, a dietary pattern celebrated by cardiologists for decades, incorporated into government guidelines, drizzled over the salads of the health-conscious everywhere. So when Christian Felipe Ruiz, a geneticist at Yale School of Medicine, started feeding mice diets enriched with o…

biologymedicinenutritiononcology

By the time researchers had catalogued 102 genes linked to autism in a single landmark paper five years ago, a quietly uncomfortable question had settled over the field. How could so many genes, doing such different jobs, produce something that looks so much like the same disorder? Some govern how chromosomes are packaged. Others regulate the junctions between neurons. Still others keep brain cel…

biologydevelopmental-biologygeneticsneurogenetics
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