Psilocybin Primes the Brain to Make Common Nerve Pain Drugs Work Far Better

Neuropathic pain is, in a sense, a glitch that refuses to self-correct. The original injury heals, or heals as much as it ever will, but the nervous system keeps insisting otherwise, flooding the brain with signals that serve no useful purpose except to make life miserable. Gabapentin is supposed to quiet that noise. For roughly half of patients it does, more or less. For the other half, it simply doesn’t work well enough, and the alternatives carry their own costs: opioids bring addiction...