autoimmunity

A massive analysis of immune cells in human tissue is yielding clues to the root cause of lung and autoimmune diseases.

A massive analysis of immune cells in human tissue is yielding clues to the root cause of lung and autoimmune diseases.

Nature Communications, Published online: 01 August 2026; doi:10.1038/s41467-026-76285-x APECED is a monogenic autoimmune disorder resulting from deleterious variants in the Autoimmune Regulator gene. Here, the authors report the cases of two patients with APECED in whom early intervention with the JAK1/2 inhibitor ruxolitinib prevented endocrine autoimmunity.

The Autoimmune Association is pleased to announce that registration is now open for the 5th Annual Autoimmune Community Summit, a free, fully virtual event designed to provide trusted information, practical tools, and meaningful support for people affected by autoimmune disease.

Sjögren's disease is a widespread chronic autoimmune disorder that attacks the body's own glands, yet its underlying disease mechanisms remain poorly understood.

The Colton Consortium for Autoimmunity today announced a new $15 million, three-year investment from the Colton Foundation to strengthen scientific leadership, expand faculty expertise, and advance collaborative research to accelerate breakthroughs in autoimmune disease across its partner institutions at New York University, Tel Aviv University, and Yale University.

The National Institutes of Health has launched its first agencywide Strategic Plan for Autoimmune Disease Research, a five-year initiative aimed at accelerating research into diseases that affect an estimated 50 million Americans and cost more than $100 billion annually.

Nature Communications, Published online: 12 May 2026; doi:10.1038/s41467-026-72975-8 CD4+ T cells are key drivers of chronic inflammation and immune-mediated tissue damage in autoimmune diseases. Here, the authors employ a mouse model of primary Sjögren disease (pSjD) and identify a subset of CD153+ CD4+ T cells responsible for inflammation and autoimmunity through interactions with CD30+ residen…

Ahead of World Lupus Day on May 10, new research from the Garvan Institute of Medical Research and UNSW Sydney helps explain why women are significantly more likely to be diagnosed with an autoimmune disease – a condition where the immune system misfires and mistakenly attacks the body's own healthy tissues.

Gillian Sandler is a life sciences investor who funds health tech companies with potential to help millions. But she began with a simple desire: Find a treatment for her sister’s autoimmune disease.

Readers of The Niche have asked me many questions about stem cells for autoimmune disease but the puzzle of why women get these conditions more often than men hasn’t come up before here. For instance, why is MS so much more common in women than men? It’s remained somewhat of a mystery over the years. […] The post Weekly reads: Xist & autoimmune disease in women, Crohn’s disease, dumb headline of …

by Gertrud U. Rey Type 1 diabetes is an organ-specific autoimmune disease that is characterized by the loss of insulin-producing beta cells in the pancreas. The loss of these cells leads to decreased insulin production (hypoinsulinemia) and increased levels of glucose in the blood (hyperglycemia). While it is still unclear what exactly causes the loss … Viruses and autoimmunity Read More »

Abstract Autoimmune inner ear disease is a well described entity. We report a case of sudden-onset sensorineural hearing loss in association with psoriatic arthritis, which has not been reported in the literature. The case satisfies the criteria for the presumptive diagnosis of autoimmune hearing loss. A high index of suspicion, with early diagnosis and aggressive treatment with steroids and/or i…