epidemiology

People often ask me for my favorite statistic. My answer changes, depending on what I’m obsessed with at any given moment. But my least favorite has been the same for years: five million children die every year. Not just because of the pain and loss that it represents, but especially because most of these deaths are avoidable. But to reduce mortality, we need to understand what children are dying…

Researchers reviewing decades of evidence conclude that alcohol plays a major role in disease and injury, affecting everything from the immune system to the brain and heart. A major new review published in Addiction paints a sobering picture of alcohol’s impact on health, linking drinking to dozens of diseases, infections, and injuries that affect nearly [...]

Nature Communications, Published online: 25 May 2026; doi:10.1038/s41467-026-73338-z Heat exposure is associated with increased emergency department visits across multiple territories, with distinct vulnerability patterns by region and cause. These findings inform targeted adaptation strategies and healthcare resource allocation under increasingly severe heat events.

Spatial and single-cell analyses of human donor pancreata showed that PanIN epithelial cells gradually acquire cancer-like molecular features, while their surrounding stromal and immune environment remains closer to normal pancreatic tissue. The findings suggest that delayed or incomplete microenvironmental reprogramming may help explain why most PanIN lesions remain indolent rather than progress…

Scientific Reports, Published online: 24 May 2026; doi:10.1038/s41598-026-51327-y Explainable AI for public health surveillance: investigating the persistent crisis of intentional injury mortality (suicide and homicide) in the Americas

A new study suggests conservative Americans experienced worse health outcomes and higher mortality rates than liberals over the last decade. Researchers attribute this widening gap to demographic shifts and a growing distrust in doctors among right-leaning individuals.

A major new study suggests that doctors may need to rethink the way obesity is diagnosed. For decades, body mass index, known as BMI, has been the standard tool used to decide whether someone is overweight or obese. But researchers now say BMI alone may miss many people who are actually at high risk of […] The post Waist size and body fat matter more than BMI alone appeared first on Knowridge Sci…

Introduction: Childhood obesity is a global public health problem with a growing prevalence in Brazil, especially among children aged 5 to 10 years monitored by the Unified Health System (SUS). Primary Health Care (PHC) serves as the gateway to care, and nurses play a fundamental role in preventing and managing this condition. Objective: To analyze the scientific evidence regarding nursing interv…

Background: Meibomian gland dysfunction (MGD) is a major contributor to evaporative dry eye disease and is characterized by obstruction of the meibomian gland ducts and altered meibum secretion. These abnormalities disrupt the tear film lipid layer, increase tear evaporation, and contribute to ocular surface inflammation and dry eye symptoms. Intense pulsed light (IPL) has emerged as a procedural…

Scientific Reports, Published online: 23 May 2026; doi:10.1038/s41598-026-51499-7 Stability analysis and numerical investigation of fractional SIR model for childhood disease transmission with vaccination

High blood pressure has long been known as one of the biggest threats to human health. Doctors often call it a “silent killer” because many people do not realize they have it until serious damage has already happened inside the body. Over time, uncontrolled high blood pressure can injure blood vessels, weaken the heart, damage […] The post Deaths From High Blood Pressure Kidney Disease Have Risen…

Cannabis use has become much more common in recent years, especially as more countries and states relax laws around marijuana. Many people believe cannabis is safer than tobacco cigarettes, especially when it is used for stress relief, pain, sleep problems, or recreation. However, a growing number of studies are raising concerns about the effects of […] The post Smoking Cannabis Every Day May Ser…

High blood pressure is one of the most common health problems in the world. Millions of people live with it every day, and many do not even know they have it. Doctors often call high blood pressure “the silent killer” because it usually does not cause clear symptoms at first. Over time, however, it can […] The post Lowering Blood Pressure Further Could Save More Lives appeared first on Knowridge …

As Europe’s leading donor countries slash budgets, the result could be more than 11.5m preventable deaths, report suggests Cuts to foreign aid budgets by the UK, France and Germany could contribute to more than 11.5 million preventable deaths by the end of the decade, according to a new report, which warns that Europe is abandoning its role as a pillar of global health and development. Three sepa…

Scientific Reports, Published online: 23 May 2026; doi:10.1038/s41598-026-53682-2 Diabetes and the risk of delayed union or non-union of fractures: evidence from a systematic review and meta-analysis

Mental health problems are becoming one of the biggest health challenges facing the world today. A major new international study has found that nearly 1.2 billion people around the globe were living with a mental disorder in 2023. This number is almost double the number recorded in 1990, showing how rapidly mental health conditions have […] The post Mental disorders now affect nearly 1.2 billion …

Abstract Purpose High-dose methotrexate is an effective treatment for adult and pediatric patients with acute lymphoblastic leukemia, osteosarcoma, and lymphoma. However, its clearance is highly variable, and delayed clearance can lead to significant toxicity. This study aimed to identify a population pharmacokinetic model that accurately characterizes high-dose methotrexate clearance in an adult…