epidemiology

A new study by researchers at UC Berkeley’s Center for Global Healthy Cities published in the Journal of the American Medical Association Network Open found that the California city of Richmond’s Office of Neighborhood Safety (ONS) was responsible for a 61% reduction in that city’s firearm homicides and injury shootings over the last 14 years. This is one of the only studies in the country to do…

A prospective UK Biobank study of 103,684 adults found that higher peak 30-minute stepping cadence was associated with lower all-cause and cardiovascular mortality across several daily step-count levels. The findings indicate that both total daily steps and the intensity of the most active stepping minutes may matter for mortality risk, particularly for people who find higher step totals difficul…

BMJ Group has published a new collection of impact stories showing how research published across its journals is helping to shape clinical practice, health policy and patient care around the world. The latest stories trace the influence of research beyond publication, from stroke studies in China that have informed clinical guidance ...

BackgroundFixed-dose combination (FDC) antihypertensive therapy is recommended by hypertension guidelines to improve adherence and blood pressure control. However, its association with healthcare utilization and health-related quality of life (HRQoL) among patients with apparent treatment-resistant hypertension (aTRH) remains unexplored. This study evaluated the association of FDC versus multi-pi…

BackgroundIsotretinoin is widely used for the treatment of acne and has been associated with musculoskeletal and connective tissue disorder adverse events However, existing research remains limited in terms of large-scale systematic investigations of these adverse effects. This study utilized the FDA Adverse Event Reporting System the Canadian Vigilance Adverse Reaction Online Database (CVARD), a…

The opioid epidemic continues to present significant public health, economic, and administrative challenges throughout the United States, with rural Kentucky experiencing some of the nation's highest rates of opioid-related morbidity and mortality. Effectively responding to this crisis requires not only adequate financial resources but also transparent governance, coordinated implementation, and …

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