Frontiers in Chemistry | New and Recent Articles

Lanthanide-based metal–organic coordination polymers (Ln-MOCPs) have been widely used in luminescent temperature sensing. Among them, Nd3+ has become a highly promising luminescent center due to its intense radiative transition properties in the first and second near-infrared regions. In this work, {[NdIMDC(H2O)4]Cl2.2H2O}n (NdIMDC, IMDC = C7H7N2O4) was synthesized using Brønsted acidic ionic liq…

IntroductionVibrational treatment increases gas nano- and microbubble content in aqueous environments. Nanobubbles stabilized by ions (bubstons) generate electromagnetic waves in the GHz range during regular oscillations and can reversibly capture secondary electrons by their boundary hydration shells. We hypothesize that these emissions facilitate long-range interactions between aqueous solution…

IntroductionAlzheimer’s disease is a complex neurodegenerative illness strongly associated with oxidative stress, which requires immediate intervention for therapeutic agents with potent antioxidant properties.MethodsIn this work, novel derivatives based on benzofuran and pyrazole scaffolds were designed and assessed for their antioxidant potential and acetylcholinesterase inhibitory activity. Th…

Solid-state silver/silver chloride pseudo-reference electrodes (PREs) are critical for miniaturized, low-cost disposable electrochemical sensors. This work systematically explores the coupling effects of substrate roughness and NaClO chlorination parameters on AgCl film microstructure and electrode electrochemical performance. Magnetron sputtering was used to deposit Cr adhesive layer/Ag function…

Hepatocellular carcinoma (HCC) is a type of malignant tumor with a low early detection rate, high morbidity, and high mortality. Therefore, early diagnosis of HCC is essential for improving patient survival and treatment outcomes. Traditional diagnostic approaches generally exhibit insufficient specificity and sensitivity. However, small-molecule fluorescent probes offer advantages, such as non-i…

Bacterial infections of biofilms are hard to treat as the matrix and physiological differences in the cells within a biofilm limit the ability of traditional antibiotics to control the growth of bacteria. We synthesized a sodium butyrate-encapsulated manganese tetrakis (4-carboxyphenyl) porphyrin hydrogen-bonded organic framework (NaB@Mn-TCPP HOF), which was used to determine its physical and che…

The medicinal plant Kedrostis nana is a relatively understudied species that belongs to the Cucurbitaceae family. It is important to understand the pharmacological potential of traditional medicinal plants such as K. nana as it could have potential in various clinical applications, especially since there have been so many advancements in the biomedical sector. Nanoparticles have also become of in…

IntroductionThe flower of Camellia petelotii (Merr.) Sealy is highly valued in Traditional Chinese Medicine, making it susceptible to adulteration with its leaves or other lower-cost adulterants. This study aims to develop a robust authentication approach to distinguish different plant parts and identify adulterated mixtures using ATR-FTIR spectroscopy integrated with chemometrics and artificial …

MXenes are commonly described by the compact formula Mn+1XnTx, yet this notation hides the variables that most strongly determine their behavior: precursor ordering, extraction pathway, vacancies, termination identity and distribution, interlayer ions and water, stacking, and transformation history. This mini review develops a solid-state chemistry framework in which MXenes are treated as chemica…

There has been a growing focus on ‘molecular chameleons’ possessing structural flexibility; compounds that can dynamically adjust their conformations depending on the characteristics of the medium to either conceal or reveal polar parts in aqueous/lipidic environments. Drug discovery has shifted in the past few decades toward more complex molecules, such as cyclic and macrocyclic peptides, as wel…

Tumor markers are critical for early cancer diagnosis and directly influence treatment outcomes and patient survival. Although enzyme-linked immunosorbent assay (ELISA) and radioimmunoassay (RIA) show satisfactory selectivity in clinical applications, their limited sensitivity for low-abundance biomarkers, relatively long assay time, and reproducibility issues have promoted the development of adv…

Disulfide-rich peptide therapeutics often exhibit compact cystine knot-like architectures that endow them with high conformational rigidity, proteolytic stability, and target specificity. Yet their intrinsic polymorphism and structural heterogeneity are difficult to resolve with conventional analytical methods, which lack sufficient power to distinguish subtle structural variants within highly co…

Iron in its elemental form has rarely been detected in the interstellar medium despite being the most abundant refractory element. The presence of iron oxides in the interstellar medium and the recent discovery of FeC in the circumstellar envelope of IRC+10,216 suggest iron-carbon-oxygen molecules as potential interstellar species. In light of this possibility, the potential energy surface of FeC…

Ultraviolet (UV) filters are essential ingredients in sunscreens and personal care products, and understanding their physicochemical properties is important for evaluating their performance and applicability. In this study, selected degree-based topological indices and their corresponding graph-energy descriptors were investigated as molecular descriptors for a set of commercially relevant UV-fil…

ObjectivesThis study analyzed clinical data from 1641 pesticide-exposed patients screened for a total of 159 pesticide compounds admitted to Shandong First Medical University Affiliated Provincial Hospital from 1 January 2023 to 31 December 2024, aiming to elucidate the multidimensional heterogeneity of pesticide co-exposure patterns.MethodsClinical information and biological samples were collect…

MXenes combine metallic conductivity, redox-active transition-metal layers, and chemically tunable surfaces, making them attractive components of negative-electrode systems for lithium-, sodium-, potassium-, zinc-, and multivalent-ion batteries. However, interpreting MXene-based negative-electrode systems only by reversible capacity obscures the coupled processes that determine their electrochemi…