cancer

Scientific Reports, Published online: 04 May 2026; doi:10.1038/s41598-026-51716-3 SARS-CoV-2 spike protein exerts an anti-cancer effect in A549 cells in association with MEG3 and BCYRN1 regulation

Cancer is often seen as a disease that grows too fast to stop. But its real danger lies elsewhere. It’s in the cells that survive. The ones that slip through treatment, adapt, and return stronger than before. These cells drive the disease—and understanding them is a key to finally stopping it.

A new study suggests that breathing in wildfire smoke over long periods of time may increase the chance of developing certain cancers. The research was presented at the American Association for Cancer Research Annual Meeting 2026 and highlights a growing concern as wildfires become more frequent. Wildfire smoke is made up of tiny particles and […] The post Study finds link between wildfire smoke …

Cancer is a global health public issue with an increasing morbidity and mortality. Ferroptosis is a form of regulated cell death characterized by iron accumulation and lipid peroxidation, providing a novel and promising strategy for cancer treatment. Plant polysaccharides possess low toxicity, minimal side effects, and significant therapeutic potential, particularly in antioxidation, immune regul…

Mucinous cancers are characterized by tumor gland cells secreting copious amounts of mucus that forms gel-like structures. Pseudomyxoma peritonei (PMP), a rare yet prototypical mucinous malignancy, exemplifies this pathology. Biologically inert mucus coats tumor cells, promoting colonization, immune evasion, and chemoresistance. Pathological mucus accumulation leads to intra-abdominal hypertensio…

(NPR) – Experts suspect several factors may be leading to these more frequent, virulent cancers: One is our greater reliance on ultra-processed foods, as well as plastics and chemicals that can leach into water and our bodies. Plus, there are … Read More

Nerve fibers within melanomas can slow the growth of these tumors, according to a study led by Weill Cornell Medicine investigators.

Nature Immunology, Published online: 29 April 2026; doi:10.1038/s41590-026-02510-w VSIG4 is a co-inhibitory receptor expressed by Kupffer cells. Here, the authors identify a direct binding interaction between VSIG4 and T cell CD5 that can calibrate CD8+ T cell responses to liver metastasis. They also design an anti-VSIG4 nanobody to enhance immune checkpoint blockade treatment of mice.

The University of Texas MD Anderson Cancer Center announced a $10 million gift from Peggy and Carl Sewell to establish the Center for Cellular Language Intelligence, a groundbreaking new research center created to understand the behavior of cancer cells at an unprecedented resolution, enabling earlier cancer detection, smarter prevention and more precise, personalized treatments.

IntroductionDysbiosis in the gut microbiome, particularly concerning the synchronous crosstalk between the gut and the liver, has been associated with various diseases. This study examines the gut microbiome's role in liver diseases among Egyptian patients, with a focus on the hepatitis C virus (HCV) and hepatocellular carcinoma (HCC), both of which are highly prevalent in Egypt.MethodsUtilizing …

Digestive system cancers (DSCs) represent a substantial global health burden. In recent years, the role of gut microbiota in the DSCs has garnered considerable attention, but its change pattern during tumor progression and the specific mechanisms are still not fully understood. We conducted a comprehensive systematic review to characterize patterns of gut microbiota dysbiosis across different DSC…

BackgroundNarciclasine has demonstrated anticancer activity at low nanomolar concentrations in various preclinical cancer models, but no clinical data in cancer patients are available. Although its biological activity and structure-activity relationships are relatively well characterized, the pharmacological properties of narciclasine have not been reported. This information will benefit the rese…

Nature Cell Biology, Published online: 27 April 2026; doi:10.1038/s41556-026-01938-4 Kozlova et al. report a functional role for NDRG1 in regulating R-loops and DNA repair, thereby linking cancer-associated fibroblast-derived extracellular matrix to chemotherapy responses in pancreatic cancer.

Nature Communications, Published online: 27 April 2026; doi:10.1038/s41467-026-72410-y Sarcopenia has been proposed as an independent risk factor for cancer incidence. Here, the authors demonstrate that muscle-secreted extracellular vesicles (EVs) suppress intestinal tumorigenesis in fly and mouse tumor models, and EVs from sarcopenic muscles lose anti-tumor activity due to age-related changes.

If you love spicy food, you are not alone. But scientists are taking a closer look at whether eating a lot of chili peppers could affect your cancer risk. Could your love of spicy food come with hidden risks? A growing body of research suggests that chili peppers, a staple in many cuisines worldwide, may [...]

dc.title: Clonal resolution of subpopulation heterogeneity underlying invasion and proliferation in triple-negative breast cancer dc.description.abstract: Intertumoral heterogeneity is a defining hallmark of triple-negative breast cancer (TNBC), driving metastatic progression and limiting treatment response, yet the mechanisms by which distinct subpopulations arise and persist are not fully chara…