cancer

[Immunity] Researchers investigated whether melanocyte-intrinsic transcriptional program(s) underlie immune tolerance to mutations resulting from UV radiation exposure.

Scientific Reports, Published online: 11 September 2026; doi:10.1038/s41598-026-70206-0 Correction: Molecular profiling of epigenetic landscape of cancer cells during extracellular matrix detachment

Nature Communications, Published online: 10 September 2026; doi:10.1038/s41467-026-77395-2 Mitochondrial transfer from astrocytes to cancer cells fuels metabolic reprogramming and enhances glioblastoma (GBM) tumorigenicity. Here this group reports a polymeric nanoplatform co-loading S-Gboxin and Galunisertib targeting GBM mitochondria and mitochondrial transfer in astrocyte-cancer cell crosstalk,…

UChicago researchers found that the MLL1 complex binds RNA indiscriminately -- and that the RNA it helps produce eventually pulls the complex apart.

Borrowing from the study of complex systems like flocks of birds and microbial communities, UChicago researchers built AI tools that compare the spatial organization of tumors -- a step toward personalized cancer treatment.

UChicago researchers found that the MLL1 complex binds RNA indiscriminately -- and that the RNA it helps produce eventually pulls the complex apart.

[Cancer Letters] Researchers used a hPSC model of neuroblastoma to show that 17q + cooperates with MYCN amplification to accelerate tumorigenesis compared to MYCN amplification alone.

Nature Immunology, Published online: 09 September 2026; doi:10.1038/s41590-026-02664-7 We found that antiviral CD8+ T cells can deputize the local innate immune system to destroy tumors. Thus, CD8+ T cells can kill by proxy, which has ramifications for cancer treatment and general mechanisms of CD8+ T cell function.

UC Santa Barbara researchers have found that triggering a stress response in glioblastoma cells, a type of aggressive

UCLA researchers have developed a way to mass-produce cancer-fighting T cells from blood stem cells found in cord blood, engineered to target a protein found in many solid tumors -- creating uniform batches instead of custom treatments for each patient.

[Nature Cell Biology] Researchers compared fibroblast diversity and epithelial–stromal interactions in pancreatitis and PDAC using human samples, mouse models, and mouse pancreatitis-derived epithelial organoids.