anxiety

A study led by researchers at King’s College London and QIMR Berghofer medical research institute analysed genetic data on anxiety symptoms in 693,869 people of European ancestry, revealing new insight into the genetic pathways involved in the condition.

Ethnopharmacological RelevanceBunium persicum is a valued traditional Persian medicinal spice used as a calming and anxiolytic agent. However, the bioactive metabolites responsible for its antioxidant and anxiolytic effects, and their underlying mechanisms, remain largely unexplored.Aim of the StudyThis study evaluated the antioxidant and anxiolytic potential of hydroalcoholic extracts and solven…

A new study finds that an inability to properly digest fructose alters the gut microbiome, triggering low-grade inflammation. This digestive disruption may contribute to anxiety and depressive behaviors by alarming the brain's immune system.

BackgroundBreast cancer patients experience significant psychological distress and marital strain during treatment. Psychological resilience may protect marital adjustment through emotional pathways, yet evidence of serial mediation mechanisms remains limited in nursing research.ObjectiveTo examine anxiety and depression as serial mediators between psychological resilience and marital adjustment.…

ObjectiveUsing a systematic review and multi-level meta-analysis, this study quantified the effects of virtual reality (VR) interventions on anxiety symptoms among women undergoing gynecological examinations or surgeries. Furthermore, it examined potential sources of effect heterogeneity and the relationship between intervention parameters and therapeutic efficacy, thereby providing an evidence-b…

Nature Human Behaviour, Published online: 28 May 2026; doi:10.1038/s41562-026-02434-3 A global analysis of more than 3,800 studies that involved over 10 million people shows that contact with nature reduces symptoms of anxiety and depression while promoting relaxation. The findings strengthen the case for integrating natural environments into mental-health strategies and urban planning policies, …

Nature Human Behaviour, Published online: 28 May 2026; doi:10.1038/s41562-026-02433-4 This systematic overview and second-order meta-analysis shows that nature-based interventions effectively reduce anxiety and depression while enhancing relaxation and positive affect.

BackgroundLarge-scale earthquakes are associated with high and persistent rates of post-traumatic stress disorder (PTSD), depression, and anxiety. Although Eye Movement Desensitization and Reprocessing (EMDR) and Cognitive Behavioral Therapy (CBT) are both guideline-recommended treatments for PTSD, direct randomized comparisons—particularly in post-disaster settings and via remote delivery—remain…

BackgroundTinnitus is closely associated with psychological factors including anxiety, depression, and sleep disturbances. However, how these variables interact to influence tinnitus severity remains poorly understood, warranting further exploration.MethodsThis retrospective study analyzed data from 285 patients with tinnitus, utilizing the Tinnitus Handicap Inventory (THI), Self-Rating Depressio…

BackgroundThe Somatic Symptom Scale-8 (SSS-8) is a brief self-report instrument assessing somatic symptom burden derived from the PHQ-15. The aims of the present study were providing updated population norms for Germany based on a new representative sample and enabling a direct comparison with the original 2012 normative sample. In addition, the study aimed to examine the psychometric properties …

Anxiety disorders affect millions of people around the world and are among the most common mental health conditions today. Many people experience anxiety from time to time, especially during stressful situations, but anxiety disorders are different. They can cause constant fear, nervousness, racing thoughts, panic, sleep problems, and difficulty concentrating. In some cases, anxiety can […] The p…

We feel more anxious when facing uncertain or unpredictable situations, but for those who score higher on autistic traits, this anxiety tends to be stronger.

Anxiety disorders are associated with impaired inhibitory neurotransmission mediated by γ-aminobutyric acid type A (GABA-A) receptors. Although benzodiazepines remain effective anxiolytics, their clinical utility is limited by sedation, cognitive impairment, tolerance, and dependence, prompting the search for mechanistically distinct GABAergic modulators. Among cannabinoid-related molecules, the …

Older adults in Colorado were drawn to edible cannabis mainly to manage sleep problems, pain, anxiety, or depression, often after concerns about conventional medicines or limited relief from other treatments. Most participants preferred THC-CBD combination products, but they remained uncertain about dosing, impairment, effectiveness, and how to choose the right cannabinoid ratio.

IntroductionIn adults, Metacognitive therapy (MCT) for Generalized anxiety disorder (GAD) has demonstrated to be an effective treatment, and even superior to comparisons in randomized controlled trials. One explanation for these results can be that MCT directly modifies dysfunctional metacognitive beliefs (including beliefs about worry as uncontrollable) which in the metacognitive model are assum…

Gemma Correll has suffered from anxiety and depression disorders since childhood, and at 16 she discovered a magical elixir that promised to make her feel better. In this extract from her new book, she shows how that promise was broken In 2018, I was in my 30s and living in Oakland, California, having moved there from the UK in 2015. I had always struggled with anxiety and panic attacks , but I w…

You've been working on your anxiety. But are you missing a piece? Understanding how it uniquely shows up for you changes everything.

BackgroundDespite growing interest in mindfulness-based interventions (MBI) for Generalized Anxiety Disorder (GAD), robust evidence for their adjunctive use alongside first-line pharmacotherapy is scarce. This study aimed to evaluate the efficacy of MBI as adjunct to pharmacotherapy in adults with GAD, assessing multidimensional outcomes.MethodsIn this randomized controlled trial, 106 adults diag…

**Insightful Psychiatry offers specialized Panic Attack Medication Management in Colorado, utilizing a Two-Pronged Strategic Approach for both Immediate Attack Intervention (fast-acting rescue meds) and Long-Term Prevention (SSRIs/SNRIs). We integrate Colorado-Specific Considerations (e.g., Altitude Effects, Wildfire Season, outdoor activity triggers) into our protocols to ensure precision and sa…

An anxiety disorder evaluation is a thorough, science-based assessment that distinguishes everyday stress from a clinical anxiety disorder like GAD, Panic Disorder, Social Anxiety, or phobias. It includes a detailed clinical interview, validated screening tools, and careful medical rule-outs to pinpoint your exact anxiety type and its root causes. You’ll walk away with clear answers and a persona…