psychiatry

Depression is often described as persistent sadness, but for many people the illness goes much deeper than feeling unhappy. One of the most painful symptoms is the loss of motivation, enjoyment, and interest in life. Activities that once brought happiness may suddenly feel empty. Hobbies become difficult to enjoy, social gatherings lose their appeal, and […] The post Parkinson’s Drug May Help Tre…

A recent study in The Journal of Clinical Psychiatry suggests that a single dose of psilocybin, paired with psychological support, may rapidly and safely reduce chronic suicidal thoughts in adults with severe, treatment-resistant depression.

For many people who suffer from depression, the condition is not just about feeling down but also about a loss of motivation and difficulty finding pleasure in activities they used to enjoy. A new study conducted in Sweden shows that a medicine used to treat Parkinson’s disease can be used as an add-on therapy to […]

IntroductionLimited research has examined participant subgroups enrolled in postpartum depression interventions. Via a cluster-randomized trial of the Mothers and Babies (MB) postpartum depression preventive intervention, we examined changes in depressive symptoms across pre-specified participant subgroups: race/ethnicity, first-time mother, language of intervention receipt, and client education.…

IntroductionDepression is a significant global health burden, with low- and middle-income countries disproportionately affected due to stigma, limited mental health resources, and imprecise diagnosis and treatment. In Latin America, reliance on non-specialized care further contributes to heterogeneous clinical outcomes. Although personalized medicine offers opportunities to improve depression man…

For many people who suffer from depression, the condition is not just about feeling down, but also about a loss of motivation and difficulty finding pleasure in activities they used to enjoy.

A new study suggests that sleep loss during pregnancy and the postpartum period may be an early driver of anxiety symptoms. Lack of sleep is often treated as an unavoidable part of pregnancy and new parenthood. But what if those restless nights are doing more than leaving parents exhausted? New research suggests sleep loss may [...]

BackgroundAutistic youth are at elevated suicide risk, yet they face multiple barriers to mental health care, including a lack of interventions adapted to their unique needs and lived experiences. In the general population, brief interventions have been shown to reduce suicide risk during the high-risk period immediately following discharge from acute care for a suicide attempt. However, no suici…

BackgroundCaregivers of individuals with severe mental disorders often face a dual burden of affiliate stigma and reduced health-related quality of life (HRQoL). However, local evidence regarding the current status of these challenges and their interrelationship remains limited.MethodsThis cross - sectional study examined the level of affiliate stigma and its association with HRQoL among primary …

Recovery-oriented social psychiatry and psychiatric rehabilitation increasingly emphasize rights, participation, community-based care, supported decision-making, supported employment, and prevention-oriented early intervention. Yet formal access to services, information, rehabilitation, legal-administrative procedures, or participation formats does not by itself ensure that people can use these r…

ObjectiveTo systematically evaluate and compare the differences in treatment outcomes between open and closed psychiatric wards for hospitalized patients with depression, and to provide evidence-based support for optimizing psychiatric ward management models.MethodsPubMed, Web of Science, China National Knowledge Infrastructure (CNKI), Wanfang Data, and VIP Database were searched for relevant lit…

The ongoing Russian-Ukrainian war has triggered a significant refugee crisis, resulting in widespread trauma, displacement, and mental health challenges among affected populations. This study aimed to explore the potential usefulness of logotherapy, a meaning-centered therapy, in addressing the mental health needs of Ukrainian refugees. The research was conducted in a naturalistic scenario of a g…

BackgroundPosttraumatic stress disorder (PTSD) is associated with impaired sexual functioning in women, but the effects of complex PTSD (CPTSD) remain unclear. This study tested three hypotheses: (1) women with CPTSD would report lower overall sexual function than women with PTSD and trauma-exposed controls; (2) the pain domain would show the largest group differences; and (3) CPTSD symptom sever…

A common treatment for mental health problems may have been fundamentally misunderstood, and could find a new use in preventing dementia

Nature Medicine, Published online: 12 June 2026; doi:10.1038/s41591-026-04465-9 Pramipexole, in patients with major depressive disorder, dysthymia or bipolar depression, reduced Snaith−Hamilton Pleasure Scale scores significantly compared to placebo.

Scientific Reports, Published online: 12 June 2026; doi:10.1038/s41598-026-45420-5 Factors associated with postpartum depression in mothers of the kangaroo mother care program in Southern Colombia: a cross-sectional study

IntroductionAction Over Inertia (AOI) is a recovery-oriented intervention designed to promote occupational engagement and support personal recovery through changes in everyday activity patterns. While AOI has been examined in Western contexts, its applicability and clinical adaptation in East Asian settings remain underexplored. This study used a mixed-methods approach to examine the feasibility …

BackgroundMajor depressive disorder (MDD) in adolescents remains a significant public health challenge. Treatment-resistant depression (TRD) affects a substantial proportion of cases and is associated with chronic symptoms, comorbidities, and elevated suicide risk. Standard treatments frequently show limited success, leading to off-label consideration of atypical antipsychotics as augmentation ag…