pediatrics

Some subgroups of children with precocious puberty--such as older girls with slowly progressing puberty--may not need the same level of testing or treatment, according to a new Endocrine Society Clinical Practice Guideline released today.
A $4 million grant from the National Institutes of Health (NIH) will help a UC Davis research team develop a lab-engineered graft to improve bladder reconstruction for children.
A joint study by the University of Oulu and Oulu University Hospital suggests that a newborn's upper lip frenulum is unlikely to be a major cause of breastfeeding difficulties.
Low concentration atropine eye drops are a safe and effective treatment for short-sightedness (myopia) in UK children, although the effects are small, suggests a clinical trial published by The BMJ today.
Boston Children's Hospital has been awarded up to $17.25 million to serve as a participating site within the Innovative Medicine and Precision Approaches to Clinical Trials (IMPACT) Network, an international effort funded through Aligning Research to Impact Autism (ARIA).
Dr. Jimmy Holder, associate professor in pediatrics at Baylor College of Medicine and Principal investigator at the Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital, and his team have received a grant for up to $17.25 million from Aligning Research to Impact Autism (ARIA) to become a part of the Innovative Medicine and Precision Approaches to Clinical Trials (IMPACT…
IntroductionIn recent years, telerehabilitation has been increasingly used to improve access to care for children and adolescents with intellectual disability (ID). However, the available evidence is still limited and highly heterogeneous. This systematic review aimed to evaluate the impact of telerehabilitation interventions on cognitive, behavioural, and functional outcomes in this population.M…
A new report in the American Journal of Human Genetics describes a novel disorder caused by biallelic loss-of-function variants in the TMEM63B gene, which results in severe lung disease.

Jennifer Rossen, MD, a pediatric ophthalmologist at Ann & Robert H. Lurie Children's Hospital of Chicago, recently received a $1 million five-year grant from the National Institutes of Health/National Eye Institute (NIH/NEI) to study the genetics of cataracts in children.
BackgroundThe role of oral bacterial lysates (OBLs) as adjuvant immunomodulatory therapy in pediatric asthma requires clarification. This systematic review and meta-analysis evaluates their efficacy and safety.MethodsWe searched eight databases for randomized controlled trials (RCTs) in children comparing standard asthma therapy plus OBLs versus standard therapy/placebo. Primary outcomes were cli…
Jennifer Rossen, MD, a pediatric ophthalmologist at Ann & Robert H. Lurie Children's Hospital of Chicago, recently received a $1 million five-year grant from the National Institutes of Health/National Eye Institute (NIH/NEI) to study the genetics of cataracts in children.
IntroductionWe investigated the effect of scalp and tongue acupuncture on the rehabilitation of children with autism spectrum disorder (ASD) and the difference in the effect between mild-to-moderate and severe children of ASD.MethodsChildren in all groups received routine rehabilitation training, including educational and therapeutic measures, while the acupuncture treatment groups also received …
ObjectiveAminoglycoside antibiotics remain essential for treating serious neonatal and pediatric infections, yet carry a well-documented risk of permanent auditory and vestibular toxicity. This review examines the pharmacological mechanisms of ototoxicity in pediatric populations, identifies those at highest risk, and assesses current prevention, monitoring, and management strategies.MethodsPubMe…
Large-scale study on children with asthma and allergies suggests no link between exposure to cats and asthma severity

From 2014 to 2024, researchers at the Indiana University School of Medicine and their global health collaborators examined the effects of an oral medication called hydroxyurea on children with sickle cell anemia in sub-Saharan Africa.
Proposals considered by government would strengthen protections for parents forced to become full-time carers Thousands of parents who are forced to become full-time carers after their child becomes seriously ill would be entitled to financial support and job protections under new “Hugh’s law” proposals being floated by the government. Hugh’s law is named after Hugh Menai-Davis, who was six when …

Routine immunizations save lives. Experts from CHLA's Child Life Program share 10 tips for an easier and less stressful experience for your child's vaccines.

When Mya Cullings was 12 years old, she thought her back pain was because of her hip-hop dancing. But as the pain worsened and breathing became difficult, her family knew something was wrong. After a visit with a chiropractor and her pediatrician, Mya was diagnosed with a severe case of scoliosis and was referred to Johns Hopkins Children's Center.
When 13-year-old Luke Branagh developed a rare and life-threatening intestinal condition during a basketball game, he was rushed to Bristol-Myers Squibb Children's Hospital at Robert Wood Johnson University Hospital, where a multidisciplinary pediatric team performed emergency surgery to save his life. After multiple procedures and intensive care, Luke made a remarkable recovery, returning to the…
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