obesity

People who begin obesity treatment with glucagon-like peptide-1 receptor agonists (GLP-1s) and then undergo metabolic and bariatric surgery achieve substantially greater weight loss than with the medications alone, according to new research presented today at the annual meeting of the American Society for Metabolic and Bariatric Surgery.

A team led by metabolism researcher Prof Timo D. Müller at Helmholtz Munich has developed a new approach for treating obesity and type 2 diabetes: a hybrid molecule uses the well-known GLP-1/GIP signalling pathway as a “door opener” and delivers an additional metabolic modulator specifically into th...

This review looks at obesity-related erectile dysfunction from a different angle. Instead of treating adipose tissue as a passive background factor, we argue that dysfunctional fat depots can actively drive the vascular, hormonal, inflammatory, and smooth muscle changes that impair erection.

Defeating obesity is rarely easy. For many people, even successful weight loss is followed by...

Patients can undergo weight loss surgery in Mexico in various cities and destinations. Juarez, Mexico, is one of the locations in the country where international patients can travel to receive bariatric surgery. It’s the largest city in Chihuahua and is known for its location near the U.S. border, which makes getting to it easy enough. […] The post Bariatric Surgery in Juarez, Mexico: Average Cos…

One in three adults in the United States are living with obesity. Obesity leads to additional health complications, including diabetes, stroke and hypertension. As obesity rates rise, bariatric surgery has also grown in popularity over the last several years. However, the costs associated with weight loss surgery are a common concern when deciding whether to […] The post Bariatric Surgery in Mexi…

Many Canadian patients ask whether undergoing bariatric surgery provides some tax benefits: Generally, Bariatric surgery — including gastric sleeve, gastric bypass, revisional surgery and others — qualifies as an eligible medical expense under the Canadian Income Tax Act, even when the procedure is performed outside of Canada. Specific Canadian Tax Code: Quick note on tax […] The post Canadian Ta…

Many patients from the United States considering undergoing bariatric surgery in Mexico ask the question: Q: Can I claim Bariatric Surgery on my tax return? A: Yes, bariatric surgery expenses are tax deductible. However, it requires meeting or exceeding certain parameters in order to get tax savings. Most patients will still opt to take the […] The post Is Bariatric Surgery Tax Deductible? appear…

Obesity is a growing health problem around the world. It is not just about body size or appearance. It is closely linked to serious diseases such as heart disease, stroke, and diabetes. These conditions can shorten life and reduce quality of life. Because of this, doctors and researchers have been trying to find the best […] The post Which obesity treatment protects the heart better? appeared fir…

Breathing is something most people do without thinking, but it can become more difficult with age. As the body grows older, the lungs naturally lose some of their strength and flexibility. However, new research shows that obesity may make this problem worse in older adults. Scientists recently shared their findings at the 2026 American Physiology […] The post Why obesity may make breathing harder…

Nature Medicine, Published online: 30 April 2026; doi:10.1038/s41591-026-04353-2 OBSCORE is a machine learning-based risk prediction tool that uses a set of clinical features to stratify individuals with a body mass index (BMI) of ≥ 27 kg m−2 by their 10-year risk of obesity-related complications, outperforming existing models. OBSCORE is generalizable across diverse populations, supporting risk-…

Nature Medicine, Published online: 30 April 2026; doi:10.1038/s41591-026-04370-1 To inform precision management of obesity, this study developed and externally validated a parsimonious model (OBSCORE) that accurately predicts the risk of 18 obesity-related complications. This was achieved by integrating thousands of clinical, molecular and other health-related characteristics assessed in 200,000 …

Data tool could help NHS prioritise who gets access to limited weight-loss medication, say scientists A new tool that can shed light on who is most at risk of obesity-related diseases could help identify people who would benefit most from weight-loss medications, researchers have said. Recent data suggests about two-thirds of adults in England are overweight or obese – a situation that has caused…

Obesity is a common health problem around the world. It happens when a person has too much body fat, and it can affect many parts of the body. Over time, obesity can increase the risk of serious diseases such as heart disease, stroke, and diabetes. Because of these risks, finding effective ways to treat obesity […] The post Surgery or new weight-loss drugs: which protects your heart better? appea…

A team led by metabolism researcher Prof Timo D. Müller at Helmholtz Munich has developed a new approach for treating obesity and type 2 diabetes: a hybrid molecule uses the well-known GLP-1/GIP signalling pathway as a "door opener" and delivers an additional metabolic modulator specifically into the target cells.

Nature, Published online: 29 April 2026; doi:10.1038/s41586-026-10427-5 GLP-1–GIP–lanifibranor, a single-molecule agonist of GLP-1R, GIPR, PPARα, PPARγ and PPARδ, shows promising therapeutic efficacy against obesity-linked metabolic dysfunction in vitro and in mouse models via synergistic incretin and PPAR activity.

A Mayo Clinic study found that both metabolic and bariatric surgery and GLP-1 medications improve cardiovascular health in people with obesity, but surgery was associated with significantly greater reductions in long-term cardiovascular risk.

A quick “gut reset” may help keep weight off after Ozempic. A new outpatient procedure could help people avoid regaining weight after stopping popular medications like Ozempic and semaglutide, according to research to be presented at Digestive Disease Week (DDW) 2026. Experts estimate that about 70% of people who discontinue these drugs regain much of [...]

Obesity is characterized by excessive energy storage in white adipose tissue, whereas increasing energy expenditure through browning the white adipose tissue represents a promising therapeutic direction. New research demonstrates that electroacupuncture can shift fat metabolism by promoting the browning of white adipose tissue in obese animals.