geriatrics

IntroductionOlder adults with depressive episodes are frequently treated in the context of psychiatric multimorbidity, somatic co-treatment, and polypharmacy, increasing their vulnerability to drug-drug interactions (DDIs) and cumulative medication-related risk. This study characterized DDI burden and exploratory prescribing risk profiles among psychogeriatric outpatients, focusing on patients wi…

BackgroundAnticholinergic drugs are commonly used as premedication in clinical practice. The effects of premedication of atropine, penehyclidine, and glycopyrrolate on postoperative delirium in older patients remain unclear.ObjectiveThe aim of this study was to observe the effects of premedication with atropine, penehyclidine, and glycopyrrolate on postoperative delirium (POD) in older patients u…

WEDNESDAY, Aug. 19, 2026 — It had been a rough few months. Cynthia Tompkins was hospitalized in May for osteomyelitis — a bone infection — then spent six weeks in a rehabilitation facility. “It was a struggle,” she...

UVA Health researchers have discovered how a form of delirium that often strikes older patients after surgery may set the stage for dementia – and identified a drug that could reverse the underlying brain changes.

BackgroundAdults aged 80 years or older frequently require peripherally inserted central catheter (PICC) placement for prolonged intravenous therapy, nutritional support, and difficult vascular access. In this oldest-old population, PICC-related bloodstream infection (PICC-CRBSI) risk may be shaped by catheter factors, frailty, nutritional depletion, immune-inflammatory imbalance, and competing e…

Many older adults take several medicines every day, including drugs to control high blood pressure. As people age and their health needs change, doctors sometimes consider whether every medicine is still necessary or whether some treatments could be reduced or stopped. This process is known as deprescribing. The goal is not simply to remove medicines, […] The post Stopping Blood Pressure Drugs Ma…

A new review suggests that healthy kidneys may play an important role in protecting eyesight as people age. Scientists found that people with chronic kidney disease were more likely to have age-related macular degeneration, a common eye disease that can gradually steal central vision. The research appears in the American Journal of Ophthalmology. Age-related macular […] The post Poor Kidney Funct…

This cohort study explores the prevalence of diabetes medication adjustment based on health status and hemoglobin A1c level among patients 65 years or older.

BackgroundThis exploratory study investigated the relationship between insomnia, neutrophil-to-lymphocyte ratio (NLR), and cognitive function in elderly Chinese cerebral small vessel disease (CSVD) patients by integrating subjective and objective sleep assessments, and to analyze the mediating effect of NLR.MethodsA total of 86 CSVD patients aged ≥ 60 years were enrolled. Sleep was evaluated by p…

Older adults with cardiovascular disease (CVD) often have coexisting cognitive impairment and frailty, conditions that can significantly affect treatment decisions, recovery, independence and quality of life and should be considered as part of an aging-informed approach to care, according to a new American College of Cardiology Scientific Statement published in JACC, the flagship journal of the A…

BackgroundInsomnia is highly prevalent in the elderly and is closely linked to “inflammaging” and neuroinflammation. While Chinese Herbal Medicine (CHM) formulations are clinically utilized, their comparative efficacy and potential modulation of the neuro-immune axis remain to be systematically quantified. This network meta-analysis (NMA) evaluated the relative efficacy of standardized CHM interv…

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