toxicology

This article reports a rare and lethal case of cyanide poisoning, aiming to explore its early diagnosis and successful treatment strategies. Upon admission, the patient presented with cardiac and respiratory arrest, deep coma, and severe metabolic acidosis. The core resuscitation measures included early mechanical ventilation, vasoactive drug support, bicarbonate therapy, and the early initiation…

Male rats that were exposed to the widely used plasticizer di-(2-ethylhexyl) phthalate (DEHP) during early development exhibited increased anxiety behavior as adults, according to a study being presented Saturday at ENDO 2026, the Endocrine Society's annual meeting in Chicago, Ill.

A new study shows that fish embryo toxicity tests using the Chinese rare minnow may provide a promising alternative to conventional acute fish toxicity tests.

IntroductionBPA exposure is known to be correlated with asthma incidence. This study aimed to investigate the molecular mechanisms underlying bisphenol A (BPA)-induced asthma.MethodsIn this study, network toxicology, machine learning, and bioinformatics approaches were integrated with differential expression analysis across multiple datasets. Clinical validation was performed using serum BPA meas…

Most microplastic research usually focuses on tissue build-up, but a new Circulation study suggests Bisphenol F (BPF) damages our heart muscle through an unexpected pathway in the gut. To determine if BPF causes harm, researchers first examined its prevalence in humans and then used germ-free mouse models and single-cell sequencing to map BPF’s path from […] The post One Microplastic’s Way to You…

"Our study highlights the need for greater attention to how prolonged device use affects chemical exposure."

A new study has raised serious concerns about a pesticide that has been widely used around the world for decades. Researchers found that children exposed to chlorpyrifos before birth showed lasting changes in brain development and had more difficulty with movement-related tasks years later. The research was published in JAMA Neurology and is being described […] The post Prenatal Pesticide Exposur…

The rapid evolution of the novel psychoactive substances market has blurred the boundaries between synthetic “designer drugs” and other emerging psychoactive products distributed outside traditional regulatory frameworks. Recently, increasing recreational and self-therapeutic interest in Amanita muscaria has led to its growing presence within the broader landscape of substances used in patterns s…

Our shell-less hen’s egg model supports the FPZ as 3R technology platform! The shell-less chicken egg model (ex ovo) is a versatile system that is cost-effective, highly reproducible, and can be rapidly applied to address a wide range of research questions in the fields of toxicity, angiogenesis, biodistribution, wound healing,...

Artificial intelligence (AI) is increasingly used to support predictive, mechanistic, and human-relevant toxicology at scale. However, its integration into regulatory science - particularly in drug development - remains uneven, because encouraging technical performance has not yet translated automatically into regulatory trust. Representative AI toxicology studies now span datasets from roughly 1…

According to a study presented today at ASPET 2026, exposure to benzalkonium chlorides (BACs) - a type of disinfectant widely used in consumer products, medical and commercial settings - caused changes in gut microbiome composition in mice, as well as the genes that encode for liver enzymes that metabolize drugs.

Since November, state has seen 47 cases of people accidentally ingesting poisonous wild mushrooms Health authorities in California’s Napa county reported that three people had been hospitalized after consuming poisonous wild mushrooms as the state continues to grapple with an “​​unprecedented outbreak” of toxic mushroom illnesses. Since November 2025, California has seen 47 cases of people accide…

IntroductionParasites are a significant threat to aquaculture, and the application of various antiparasitic chemicals by aquafarmers is a widely practiced strategy to control them. Few antiparasitic drugs are toxic to hosts at higher concentrations and may be genotoxic to them. Genotoxicity tests have been successfully used as indicators of the toxicity of several drugs and environmental pollutan…

Independent scientists who reviewed the results said most samples were contaminated with Pfas or phthalates The Trump administration announced earlier this month that hundreds of baby formula samples it tested for toxic chemicals “meet a high safety standard”, but public health advocates warn this claim contradicts data showing a majority were contaminated with dangerous substances, such as Pfas …

Toxicology for impurity mapping in pharmaceuticals is a critical, regulatory-driven process designed to establish the biological safety of impurities found in... The post Toxicology & Impurity Mapping UK Brands appeared first on Food Research Lab .

IntroductionEnvironmental contamination by polycyclic aromatic hydrocarbons (PAHs) has increased in recent decades, intensifying the exposure of organisms in wetland ecosystems. Anthracene, due to its chemical stability and persistence, represents a potential risk to herbivorous insects associated with aquatic vegetation.MethodsThe toxicity of anthracene to the semi-aquatic grasshopper Cornops aq…