toxicology

Our shell-less hen’s egg model supports the FPZ as 3R technology platform! The shell-less chicken egg model (ex ovo) is a versatile system that is cost-effective, highly reproducible, and can be rapidly applied to address a wide range of research questions in the fields of toxicity, angiogenesis, biodistribution, wound healing,...

Artificial intelligence (AI) is increasingly used to support predictive, mechanistic, and human-relevant toxicology at scale. However, its integration into regulatory science - particularly in drug development - remains uneven, because encouraging technical performance has not yet translated automatically into regulatory trust. Representative AI toxicology studies now span datasets from roughly 1…

According to a study presented today at ASPET 2026, exposure to benzalkonium chlorides (BACs) - a type of disinfectant widely used in consumer products, medical and commercial settings - caused changes in gut microbiome composition in mice, as well as the genes that encode for liver enzymes that metabolize drugs.

Since November, state has seen 47 cases of people accidentally ingesting poisonous wild mushrooms Health authorities in California’s Napa county reported that three people had been hospitalized after consuming poisonous wild mushrooms as the state continues to grapple with an “​​unprecedented outbreak” of toxic mushroom illnesses. Since November 2025, California has seen 47 cases of people accide…

IntroductionParasites are a significant threat to aquaculture, and the application of various antiparasitic chemicals by aquafarmers is a widely practiced strategy to control them. Few antiparasitic drugs are toxic to hosts at higher concentrations and may be genotoxic to them. Genotoxicity tests have been successfully used as indicators of the toxicity of several drugs and environmental pollutan…

Independent scientists who reviewed the results said most samples were contaminated with Pfas or phthalates The Trump administration announced earlier this month that hundreds of baby formula samples it tested for toxic chemicals “meet a high safety standard”, but public health advocates warn this claim contradicts data showing a majority were contaminated with dangerous substances, such as Pfas …

Toxicology for impurity mapping in pharmaceuticals is a critical, regulatory-driven process designed to establish the biological safety of impurities found in... The post Toxicology & Impurity Mapping UK Brands appeared first on Food Research Lab .

IntroductionEnvironmental contamination by polycyclic aromatic hydrocarbons (PAHs) has increased in recent decades, intensifying the exposure of organisms in wetland ecosystems. Anthracene, due to its chemical stability and persistence, represents a potential risk to herbivorous insects associated with aquatic vegetation.MethodsThe toxicity of anthracene to the semi-aquatic grasshopper Cornops aq…

Exposure to one of the most toxic forms of mercury (methylmercury) may also disrupt the body's metabolic health, according to the findings of a new international study. The research, involving University of Bristol scientists and published in Chemical Research in Toxicology, found the element may have wider health effects than previously known.

Scientific Reports, Published online: 06 May 2026; doi:10.1038/s41598-026-51780-9 Life-stage-specific resistance to imidacloprid and thiamethoxam in COI-confirmed Bemisia tabaci MEAM1 and adult detoxification enzyme activity

Liver and kidney, as the core metabolic detoxification organs of human body, rely on specific biofilm barrier and metabolic enzyme system to form metabolic barrier respectively. This metabolic barrier is the key defense line to resist the invasion of drugs and environmental poisons. There are significant differences in the structural function and toxic response mechanism of the metabolic barrier …

Many people use products every day without thinking about the chemicals inside them. Nonstick pans, stain-resistant carpets, and water-resistant clothing all contain substances designed to make life easier. However, some of these substances may come with hidden health risks. A group of chemicals called PFAS has recently attracted attention from scientists. These chemicals are widely […] The post …

Fuzi, the processed lateral root of Aconitum carmichaelii Debeaux (Ranunculaceae), is a vital yet highly toxic botanical drug in traditional Chinese medicine. However, its narrow therapeutic window, driven by highly toxic diester-diterpenoid alkaloids (DDAs), necessitates rigorous processing. Adhering to the four pillars of best practice in ethnopharmacology, this review systematically evaluates …

The study identifies critical windows of metal exposure via baby teeth, revealing impacts on brain development and behavior in children and adolescents.

New studies highlight sex differences in biological responses to PCB exposure and highlight the protective effect of folic acid