ophthalmology

Scientists identified a new vision condition linked to a gene already connected to a different vision-loss disease. While the previously identified disease causes loss of central vision, the new condition affects peripheral and night vision.

Scientific Reports, Published online: 11 September 2026; doi:10.1038/s41598-026-71306-7 OCTA-based evaluation of retinal microvascular changes during recombinant GH therapy in children with GH deficiency

PurposeAcute zonal occult outer retinopathy (AZOOR) is a rare outer retinal disorder that may mimic inherited retinal dystrophy. This study revises a retrospective AZOOR case series by integrating retinal oximetry as a metabolic imaging biomarker and comparing the oximetry findings with retinitis pigmentosa (RP) and healthy control data.MethodsSeven consecutive patients diagnosed with AZOOR at HO…

ObjectiveTo study the improvement of subjective visual quality in patients with a small amount of residual refraction and poor visual quality after small incision ienticule extraction (SMILE) surgery through visual cortex training.MethodsEleven subjects (22 eyes) aged 18–40 years who had undergone SMILE >6 months previously were prospectively enrolled. Subjects were trained 30 times, with the pre…

As part of an effort to understand the molecules and mechanisms that regulate transendothelial migration in different vascular beds of the body, researchers focused on the blood vessels of the retina, part of the blood-brain barrier.

A large study of nearly 74,000 men suggests that long-term use of tadalafil, best known as Cialis, may be linked to a higher risk of glaucoma and other eye pressure problems. Men prescribed the drug for urinary symptoms caused by an enlarged prostate were 22% more likely to develop glaucoma, 32% more likely to develop ocular hypertension, and 33% more likely to be diagnosed with primary open-angl…

Inherited retinal dystrophies (IRDs) represent heterogeneous genetic eye disorders frequently linked to RPE65 mutations. Voretigene neparvovec (VN, Luxturna), an AAV2-mediated gene therapy, remains the sole approved drug for biallelic RPE65-associated IRDs. This study presents 3-, 6- and 22-month follow-up findings of the first mainland Chinese patient with compound heterozygous RPE65-related Leb…

Nation's largest physician organization adopts policy calling for insurance coverage for treatments that can slow its progression in children.

Gene Therapy, Published online: 02 September 2026; doi:10.1038/s41434-026-00640-2 Optogenetic vision restoration: translational barriers and emerging therapeutic strategies

Joel S. Schuman, MD, FACS, has been selected as the recipient of the 2027 RPB David F. Weeks Award for Outstanding Vision Research for his transformative contributions to ophthalmic imaging, glaucoma research, and vision science.

Dry eyes are a very common chronic eye condition among women in perimenopause and beyond. Here's why you shouldn't ignore it.

Scientific Reports, Published online: 30 August 2026; doi:10.1038/s41598-026-68699-w Effect of residual spherical equivalent on visual outcomes of trifocal intraocular lens implantation in patients with cataracts across different refractive states

BackgroundIntravenous methylprednisolone pulse (IVMP) therapy is the first-line treatment for active moderate-to-severe and very severe thyroid-associated ophthalmopathy (TAO). IVMP-induced sinus bradycardia has not been previously reported in patients with TAO in the published English-language literature. This study aimed to determine the prevalence and characteristics of IVMP-induced bradycardi…

PurposeTo determine which subgroup of children would best benefit from 0.01% atropine eyedrop.MethodsThis post hoc secondary analysis assessed 68 subjects. Placebo for the first year and 0.01% atropine eye drops for the second year. According to the annual spherical equivalent progression (SEP) during the first year, subjects were subdivided into three groups: slow, moderate and fast (annual SEP …

A dual stem cell scaffold improved vision and eye surface scores in a small first-in-human trial for aniridia-related keratopathy. For people with ARK (aniridia-related keratopathy), progressive damage to the eye’s surface can gradually cloud the cornea and severely reduce vision. In a first-in-human clinical trial at Moorfields Eye Hospital and University College London (UCL), a […]

The editorial was authored by Jacque L. Duncan, MD, professor of ophthalmology and chair of the Department of Ophthalmology, University of California, San Francisco, who did not participate in the PRIMA study. In a press release issued by Science Corporation, the company described the implant as “consisting of a tiny wireless chip implanted in the […]

A dual stem cell scaffold improved vision and eye surface scores in a small first-in-human trial for aniridia-related keratopathy. For people with ARK (aniridia-related keratopathy), progressive damage to the eye’s surface can gradually cloud the cornea and severely reduce vision. In a first-in-human clinical trial at Moorfields Eye Hospital and University College London (UCL), a [...]

Glaucoma is an eye disease that causes progressive damage to the optic nerve, leading to loss of sight. One major risk factor is an increase in intraocular pressure (IOP), or the pressure inside the eye.