Diagnostics World | Researchers at The University of Texas MD Anderson Cancer Center are investigating whether immune-system biomarkers could help identify cancer patients most likely to benefit from rapid-acting psychedelic treatments for depression. Researchers examined whether these rapid-acting antidepressants share biological pathways that could serve as biomarkers for future treatment strat…
Diagnostics World | Analyzing genetic changes in cancer cells provides insight into how tumors develop and help with developing treatment through precision oncology. Long-read sequencing can help, but there is still a higher error rate compared to short-read sequencing. Researchers at The University of Hong Kong addressed this gap with ClairS, a tool designed to identify small cancer-related gene…
Diagnostics World | The worried well the world over now have readily accessible and easy to self-administer home tests for assessing their risk for diabetes and chronic kidney disease, thanks to the computational skills of a pair of researchers at DTU Sustain, based at the Technical University of Denmark. The new online tools focus on a small number of parameters identified by artificial intellig…
Diagnostics World | Researchers have uncovered evidence that the brain coordinates information across multiple timescales without requiring those processes to be synchronized moment to moment, a finding that could eventually inform new approaches to neurological and psychiatric diagnostics.
Diagnostics World | Human Longevity last week announced the availability of Genomics for All, a clinical-grade whole genome sequencing product priced at $599. The offering sequences all 6.4 billion base pairs of an individual's DNA and delivers AI-interpreted results through the HLI app, with no clinic visit required.
Diagnostics World | PacBio made several announcements this week: Mark Van Oene is the new President and CEO for the company and new chemistry and software are available for its Vega systems. Both changes aim to position the company for wider platform adoption across labs and research areas.
Diagnostics World | Blood-based biomarkers predicting when symptoms of amyotrophic lateral sclerosis (ALS) will emerge are expected to catapult the medical research community forward in the quest to prevent the fatal neurodegenerative disorder. Researchers from the University of Miami Miller School of Medicine have been spearheading the Pre-Symptomatic Familial ALS (Pre-fALS) study collecting lon…
Diagnostics World | Smartwatches could one day do more than track steps, sleep, and heart rate. Researchers at the University of California San Francisco (UCSF) are working with Samsung to determine whether physiological data collected passively by a smartwatch can help identify early changes in cognitive function.
Diagnostics World | Fresenius expands its access to innovation networks through its own corporate venture capital fund over the next five years; Transcripta Bio's closed-loop discovery engine is designed to use transcriptomic signature matching to identify drugs whose molecular signatures are the inverse of patient-derived disease signatures; and more.
Diagnostics World | Myriad Genetics announces the full commercial launch of FirstGene Multiple Prenatal Screen; Amprion reaches an agreement with Decathlon Capital Partners for a significant growth-funding investment; and more.
Diagnostics World | Growing momentum in biomarker discovery, advancing analytical technologies, and a shift toward personalized medicine have created unprecedented possibilities for diagnostic development. The pace at which this progress translates to novel, widely adopted, clinically validated diagnostic tools remains slow, but not for lack of innovation.
Diagnostics World | Digestive sensations profoundly affect mental health through the bidirectional gut-brain axis, and in the case of anorexia nervosa (AN) tends to do so at crisis proportions. The disorder has one of the highest mortality rates of any psychiatric disorder with suicide being the leading cause of death.
Diagnostics World | Indole-3-propionic acid (IPA) is increasingly recognized as a critical chemical shield and promising biomarker for gut inflammation. Levels of IPA are starkly deficient in the blood of patients with active ulcerative colitis (UC), but the gold standard measurement technique of liquid chromatography-mass spectrometry (LC-MS) is costly and requires highly trained technicians to …
Diagnostics World | Much like the trajectory of infectious disease diagnostics was changed by PCR and molecular methods, Epi One is looking to alter the course of cancer diagnostics with direct, highly sensitive molecular detection of specific epigenetic biomarkers of multiple malignancies. First out of the gate will be a prostate cancer re-biopsy decision tissue-based assay, immediately followed…
Diagnostics World | Researchers from Washington University School of Medicine, St. Louis have showed that elevated levels of a set of circular RNAs (circRNAs) in the blood nearly tripled patients’ risk of developing Alzheimer’s Disease (AD) symptoms, suggesting these molecules are more sensitive to symptom onset than traditional AD biomarkers.
Diagnostics World | Researchers in London have identified a 14-protein blood signature predictive of lung cancer risk more than five years before a clinical diagnosis. If the proteomics panel makes its way to routine clinical practice, it could prove invaluable in flagging individuals likely to benefit from preventive screening.
Diagnostics World | Thanks to several key advances in deep learning architecture, optical coherence tomography (OCT)—one of the most obtained medical images in the world—can now be used to predict disease one patient at a time. The people who stand to benefit are not only those suffering from common retinal diseases, but also conditions such as heart attack, stroke, and kidney failure simply by a…
Diagnostics World | A new type of digital twin model of the brain, designed specifically for children with autism spectrum disorder, has been developed by researchers in Italy in hopes of enabling targeted treatment with transcranial magnetic stimulation at the exact location in the brain where neural circuits are misfiring.
Diagnostics World | Spot Biosystems emerged from stealth and published a study on Duchenne muscular dystrophy; NewLimit aims to accelerate liver recovery from injury and improve tolerance of dietary and alcohol-related stress in preclinical models; and more.
Diagnostics World | Labcorp announced the nationwide availability of ColoSense; Hartwig Medical Foundation and Ultima Genomics announce an expansion of their strategic collaboration; the University of Texas MD Anderson Cancer Center join a global consortium dedicated to eliminating cervical cancer worldwide; and more.
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