Diagnostics World | Indole-3-propionic acid (IPA) is increasingly recognized as a critical chemical shield and promising biomarker for gut inflammation. Levels of IPA are starkly deficient in the blood of patients with active ulcerative colitis (UC), but the gold standard measurement technique of liquid chromatography-mass spectrometry (LC-MS) is costly and requires highly trained technicians to run the equipment, limiting its use to specialized research cohorts and clinical trials.
