psychobiotics

BackgroundChronic constipation and depression are highly prevalent worldwide. These two conditions frequently co-occur in clinical practice. Accumulating evidence indicates that gut microbiota dysbiosis mediates this comorbidity through the microbiota-gut-brain axis (MGBA).MethodsThis narrative review systematically summarizes current research on MGBA bidirectional communication mechanisms, gut m…

Human breastmilk is a rich source of beneficial microbiota and bioactive compounds, yet its potential as a reservoir of psychobiotics remains underexplored. In this study, breastmilk samples were aseptically collected from healthy lactating mothers and cultured using MRS media. A total of 188 bacterial isolates were screened for gamma-aminobutyric acid (GABA) production using monosodium glutamate…