wound-healing

Scientists have redefined how the key blood‑clotting protein fibrinogen behaves when it contacts air, overturning two decades of scientific consensus on wound healing.

Placentas contain a rich amount of nutrients and stem cells, but there’s a difference between eating it at home for wellness and using it in the clinic to improve wound healing.

Diabetic foot ulcers are among the most serious complications of diabetes because prolonged inflammation, poor circulation, and defective angiogenesis can leave wounds open for months and increase the risk of infection and amputation.

Any minor cut or scrape sets the body's natural healing process in motion. However, deep wounds are far more vulnerable to bacterial infection and the accumulation of harmful molecules called reactive oxygen species (ROS) that damage cells and disrupt normal repair mechanisms. These factors can sign...

Any minor cut or scrape sets the body's natural healing process in motion. However, deep wounds are far more vulnerable to bacterial infection and the accumulation of harmful molecules called reactive oxygen species (ROS) that damage cells and disrupt normal repair mechanisms.

IntroductionThe pathology of diabetic foot ulcer (DFU) is characterized by keratinocyte dysfunction, non-resolving inflammation, and oxidative stress. We aim to investigate the effects and mechanisms of piroxicam on DFU healing through regulating mitochondrial function and suppressing inflammation.MethodsDFU was established in male C57BL/6 J mice and ovariectomized female mice. Piroxicam (1% or 0…

BackgroundResina Draconis, a traditional Chinese herbal medicine with wound‐healing properties, has been increasingly used as an adjunctive treatment for diabetic foot ulcers (DFUs). This systematic review and meta‐analysis aimed to evaluate the efficacy and safety of Resina Draconis in the treatment of DFUs.MethodsFive electronic databases were systematically searched for randomized controlled t…

Chronic wounds in dogs represent a significant clinical challenge due to persistent inflammation and impaired tissue repair. This case series describes four canine patients with chronic, treatment-resistant cutaneous wounds treated with plant-derived exosome-like nanovesicles (PNELs) delivered via ice-needling technology (IN). Three dogs presented with post-surgical wound dehiscence and one dog w…

Chronic wounds remain a major healthcare challenge, especially for people with diabetes, who often experience delayed healing, persistent inflammation, and a higher risk of infection.

Infected wounds pose a significant medical challenge, often leading to delayed healing and complications due to bacterial biofilms and excessive inflammation.

The needles start out straight, packed in a tidy array no wider than a fingertip. Press the patch onto warm skin and they begin to move. Within two minutes they have hooked themselves into a coil, like dozens of tiny fingers tightening their grip, pulling the edges of a wound together from the inside. Nobody is turning a screw or pulling a thread. The needles are simply responding to the heat of …

A Bandage That Makes Its Own Gas Could Help Stubborn Wounds Heal Dr. Cristine Heaps, interim head of the Department of Veterinary Physiology and Pharmacology, poses with a microscope in her laboratory at the Texas A&M College of Veterinary Medicine and Biomedical Sciences. A blister on the heel. A small cut that catches on a sock. For most of us these are nothing, gone in a week and forgotten. Fo…

Considering the enormous scale of the global wound dressing market, optimized wound dressings have tremendous market prospects. Chitosan (CS) shows excellent antibacterial and hemostatic activity, and hyaluronic acid (HA) has good biocompatibility, hygroscopicity, and anti-inflammatory activity. For these reasons, both are widely used as wound dressings. In this review, we systematically discuss …

Chronic non-healing wounds, including diabetic ulcers, venous leg ulcers, and pressure ulcers, represent a significant clinical burden worldwide, associated with major economic costs and impaired quality of life. Although stem cell–based therapies have shown regenerative potential, recent accumulating evidence indicates that their therapeutic effects are primarily mediated by paracrine signaling …

Nature Biomedical Engineering, Published online: 27 May 2026; doi:10.1038/s41551-026-01687-7 Engineered cells embedded in a removable wound patch provide sustained local cytokine delivery, reshaping immune and tissue repair programs to speed healing in rodent and porcine excisional wound models.

Introduction: Metabolic disorders, particularly diabetes mellitus, can lead to the formation of chronic wounds, slowing healing processes. A key factor impeding wound healing is the decreased production of endogenous nitric oxide (NO) due to a hyperglycemic microenvironment. Nitric oxide (NO) is a key signaling molecule produced by three different isoforms of nitric oxide synthase (NOS) – iNOS, e…

A new living bandage accelerates healing across multiple wound types, researchers report.

Impaired mitophagy and the accumulation of damaged mitochondria are key drivers of endothelial cell (EC)dysfunction in diabetic wounds.