Considering the enormous scale of the global wound dressing market, optimized wound dressings have tremendous market prospects. Chitosan (CS) shows excellent antibacterial and hemostatic activity, and hyaluronic acid (HA) has good biocompatibility, hygroscopicity, and anti-inflammatory activity. For these reasons, both are widely used as wound dressings. In this review, we systematically discuss the characteristics, bioactivities, and commercial wound healing products involving CS and HA. Their