neuroprotection

BackgroundLycium barbarum glycopeptide (LbGp) has been reported to exert neuroprotective effects, yet its role in chronic ocular hypertension (COH) and the underlying mechanisms remain unclear. This study investigated whether LbGp protects against COH-induced retinal damage by inhibiting pyroptosis.MethodsA COH rat model was established, and the animals were randomly assigned to model, LbGp, VX-7…

Evaluation of the neuroprotective effects of synthetic erythropoietin derivatives in a mouse model of mild and moderate hypoxic-ischemic encephalopathy DOI: https://doi.org/10.18413/rrpharmacology.12.1071Abstract Introduction: Hypoxic-ischemic encephalopathy (HIE) is a leading cause of neonatal brain injury and long-term neurodevelopmental impairment, and current therapies only partially prevent …

Our Bridging the Gap series makes a return! For each post, we interview women in neuroscience about health inequalities and the research aiming to close these gaps. In this article, we focus on neuroprotection in premature babies, and the communication tool that Maria Pureza Laudiano-Dray and her team are implementing to protect preterm infants’ developing brains during the earliest and most vuln…

Since Ed Hall and colleagues first discovered that female gerbils were relatively protected from global cerebral ischemia, compared with their male counterparts, in the early 1990s (Hall et al., 1991), gender differences […]