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New cellular immunotherapy approach for Alzheimer’s disease shows promise in mice

New findings in mice shed light on brain’s response to the keto diet, long known to help treat some patients with epilepsy

Alzheimer’s disease, the most common type of dementia in older adults, begins in the hippocampus, a deep brain structure that plays a central role in learning and memory. Studying the progression of this chronic disease requires high-resolution monitoring of the deep brain over extended periods, which is challenging due to technical limitations. Song Hu, PhD, […]

Estimating the onset of symptoms could speed development of preventive treatments

The impact of wildfire on the risk of developing a migraine; using AI to improve childhood cancer outcomes; managing pain in people with sickle cell disease; and understanding the spread of herbicide resistance — these are some of the projects supported by the most recent Ignite Interdisciplinary Grant awards.   Ignite grants are part of WashU’s […]

Researchers at WashU Medicine have identified a potent pathway that begins in the brain and leads to loss of all body fat without reducing food intake. The study is reported in Nature Metabolism. The team — led by senior author Erica L. Scheller, DDS, PhD, an associate professor in the Division of Bone and Mineral Diseases in […]

Study in mice points to a promising new approach for Alzheimer’s disease

Patients receiving treatments targeted to the network, rather than to nearby brain regions, experience larger improvements

Jin-Moo Lee, MD, PhD, the Andrew B. & Gretchen P. Jones Professor of Neurology and head of the Washington University School of Medicine in St. Louis Department of Neurology, and Jeffrey R. Millman, PhD, a professor of medicine at WashU Medicine and of biomedical engineering, have each been selected as recipients of the prestigious Dr. Ralph and […]

Black Americans die younger than their white counterparts, with an estimated 1.63 million “excess” deaths having occurred between 1999 and 2020, according to research in the Journal of the American Medical Association. These excess deaths are predominantly attributable to chronic conditions such as heart disease and cancer. In a new study published in JAMA Network Open, researchers…